If you would live long, choose your parents well

Trends in Genetics : TIG
A Cournil, T B Kirkwood

Abstract

Human longevity appears to have a modest but significant heritable component. A recent study in Iceland has added to this evidence by making a unique assessment based on records for an entire population. Although the evidence for inheritance of human lifespans appears robust, there remains considerable uncertainty about the extent of the genetic versus the nongenetic contribution and about the importance of gene-environment interactions. Sex-specific patterns of transmission of lifespan between parents and offspring might provide clues to the basis of lifespan heritability, but the reported patterns are neither conclusive nor consistent.

References

Jan 1, 1978·American Journal of Medical Genetics·P Philippe
Nov 1, 1993·Journal of Gerontology·M McGueB Harvald
Jul 1, 1993·Human Genetics·F SchächterT Kirkwood
Oct 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·G J Lithgow
Oct 23, 1997·Science·C E Finch, R E Tanzi
Nov 21, 1998·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·B LjungquistN L Pedersen
Jun 22, 1999·Nature·T Ligtenberg, H Brand
Aug 5, 1999·Perspectives in Biology and Medicine·B A CarnesD Grahn
Oct 20, 2000·European Journal of Human Genetics : EJHG·H GudmundssonK Stefánsson
Nov 23, 2000·Nature·T B Kirkwood, S N Austad
Aug 11, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·David A GunnRudi G J Westendorp

❮ Previous
Next ❯

Citations

Apr 4, 2003·Aging Clinical and Experimental Research·Nicholas P HaysSusan B Roberts
Oct 7, 2004·Aging Clinical and Experimental Research·Giovanni Mario PesCalogero Caruso
Aug 9, 2013·Human Genetics·Angela R Brooks-Wilson
May 24, 2005·Mechanisms of Ageing and Development·Andrew M Prentice
Oct 1, 2003·Trends in Endocrinology and Metabolism : TEM·Thomas B L Kirkwood
Mar 1, 2002·Mechanisms of Ageing and Development·Thomas B L Kirkwood
Sep 23, 2003·Mechanisms of Ageing and Development·Pauline LeeErnest Beutler
Aug 15, 2002·Trends in Genetics : TIG·Thomas B L Kirkwood
Jan 5, 2002·Experimental Gerontology·E L OstlerR G A Faragher
Feb 13, 2003·Experimental Gerontology·Domenico LioCalogero Caruso
Mar 4, 2003·Nature Reviews. Molecular Cell Biology·Thomas B L KirkwoodDarren J Wilkinson
Apr 13, 2006·Rejuvenation Research·Letizia ScolaCalogero Caruso
Apr 30, 2010·Rejuvenation Research·Florinda ListìGiuseppina Candore
Jun 19, 2013·Rejuvenation Research·Alexander M Kulminski
Sep 27, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Thomas PerlsIrma T Elo
Oct 5, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Martin GögeleMatthias Wjst
Feb 20, 2013·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Evangelia E AntoniouDavid Llewellyn
Oct 22, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Zhen LiJoyce Royland
Jul 19, 2008·Shock·Vanessa NomelliniElizabeth J Kovacs
Jun 14, 2003·BMJ : British Medical Journal·Thomas B L Kirkwood
Jan 15, 2005·Journal of Epidemiology and Community Health·Jean AdamsDavid Forman
Aug 15, 2009·PloS One·Julius Halaschek-WienerAngela R Brooks-Wilson
Nov 8, 2012·PloS One·Daniele CampaRoberto Barale
Dec 6, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Alexander M KulminskiAnatoliy I Yashin
Nov 1, 2005·Proceedings of the National Academy of Sciences of the United States of America·Katarina NordfjällGöran Roos
Jun 26, 2002·Proceedings of the National Academy of Sciences of the United States of America·Anne M BronikowskiMarc Tatar
Aug 17, 2010·Ageing Research Reviews·Cinnamon S BlossNicholas J Schork
Feb 27, 2010·Mechanisms of Ageing and Development·Anatoli I YashinIrma T Elo
Jul 5, 2005·EMBO Reports·Thomas B L Kirkwood
Oct 23, 2015·Disease-a-month : DM·Martin S Lipsky, Mitch King
May 22, 2004·Aging Cell·Jesper GraakjaerJosé-Arturo Londoño-Vallejo
Apr 17, 2004·Journal of the American Geriatrics Society·Toshiki OhtaOrie Nakamura
Dec 29, 2007·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Jeremy M SilvermanJoy Y Wang
Jan 31, 2007·Annals of the New York Academy of Sciences·Giuseppina CandoreCalogero Caruso
Feb 22, 2011·The Psychiatric Clinics of North America·Cinnamon S BlossNicholas J Schork
Aug 2, 2005·Current Opinion in Immunology·David Allman, Juli P Miller
Sep 17, 2015·Nature Reviews. Molecular Cell Biology·Bérénice A BenayounAnne Brunet
Jan 30, 2008·Journal of Internal Medicine·T B L Kirkwood
Jul 10, 2009·Health Economics·Alain TrannoyMarion Devaux
Jan 1, 2012·Worm·Bérénice A Benayoun, Anne Brunet
Mar 1, 2005·Cell·Thomas B L Kirkwood

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Human Genetics : EJHG
H GudmundssonK Stefánsson
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
R A KerberR M Cawthon
© 2021 Meta ULC. All rights reserved