IFN-Independent STING Signaling: Friend or Foe?

Immunity
Volker BöhnertLingyin Li

Abstract

In this issue, Wu et al. demonstrate the importance of the neglected interferon (IFN)-independent STING signaling axis in mice. They find that although this axis is important for antiviral HSV-1 resistance, it has a pro-cancer role by promoting T cell death.

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