IgA antibodies to Chlamydia trachomatis and seminal parameters in asymptomatic infertile males

Archives of Andrology
S Penna VideaúN Salazar

Abstract

Prevalence of IgA antibodies to Chlamydia trachomatis in semen samples from infertile men was estimated and its clinical meaning is discussed. The ejaculate of 102 infertile men without any symptom of genital infection was studied, and seminal alterations were classified according to WHO criteria. Antichlamydial IgA antibodies were detected using a solid-phase, enzyme-linked immunoassay (ImmunoComb II Chlamydia trachomatis monovalent IgA) and related to sperm count, motility and membrane integrity, seminal leucocyte count, and past history of sexually transmitted disease (STD). Prevalence of IgA antibodies to C. trachomatis was 23%. There was no relationship between IgA antibodies and the sperm variables or leucocyte count in semen. However, a strong association between antichlamydial IgA antibodies and the antecedent of STD was found (p < .005; OR = 6). IgA antibodies to C. trachomatis did not cause alterations in sperm function and they were not associated with inflammatory response. However, these antibodies in semen of asymptomatic infertile men would indicate a risk of C. trachomatis infection for the couples of those patients.

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Citations

Jul 1, 2011·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Ashok Agarwal, Lucky H Sekhon
Feb 24, 2006·Asian Journal of Andrology·Giorgio Cavallini
Jun 2, 2009·European Urology·Sandra MazzoliRiccardo Bartoletti
May 6, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Donatella PellatiDecio Armanini
Jul 1, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Zdenek VeznikVit Unzeitig
Feb 12, 2004·Andrologia·G F GonzalesE Bustos-Obregón
Aug 25, 2010·International Journal of Andrology·A Eley, A A Pacey
Aug 26, 2016·Systems Biology in Reproductive Medicine·Ruth MoralesRafael Bernabeu
May 16, 2008·Biology of Reproduction·Kelly A Cunningham, Kenneth W Beagley
Oct 27, 2017·International Journal of STD & AIDS·M MoazenchiA Mohseni Meybodi
May 15, 2020·Reproductive Biology and Endocrinology : RB&E·Leila KoosheshMohammad Hussain Nasr-Esfahani

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