PMID: 3992908Feb 1, 1985Paper

IgE and IgG antibodies to flea antigen in differing dog populations

Veterinary Immunology and Immunopathology
R E Halliwell, S J Longino

Abstract

A radioimmunoassay was developed for the detection of IgG and IgE canine antibodies against partially purified flea antigen. Low background levels were found in flea naive dogs, but high levels of both IgE and IgG antibodies were found in many sera from dogs with clinical flea hypersensitivity. In sera from non-allergic dogs exposed chronically to fleas, IgE levels differed little from background, and levels of IgG anti-flea antibodies were much lower than those from the flea allergic group. The results suggest that chronic flea exposure may result in partial or complete tolerance rather than hyposensitization in the commonly accepted sense.

References

Jun 30, 1975·Annals of the New York Academy of Sciences·R E Halliwell
Nov 1, 1979·International Journal of Dermatology·M Kieffer, S Kristensen
Oct 1, 1978·The Journal of Allergy and Clinical Immunology·R E Halliwell, G A Kunkle
Dec 1, 1961·Proceedings of the Society for Experimental Biology and Medicine·E BENJAMINIL KARTMAN

❮ Previous
Next ❯

Citations

Jun 1, 1987·Veterinary Immunology and Immunopathology·R E Halliwell, K R Schemmer
Dec 1, 1987·Veterinary Immunology and Immunopathology·R E HalliwellJ G Nesbitt
Jan 1, 1995·Veterinary Immunology and Immunopathology·P B HillD J DeBoer
Mar 1, 1994·Veterinary Parasitology·M W Dryden, M K Rust
Oct 1, 1996·Veterinary Immunology and Immunopathology·H A JacksonR E Halliwell
Jan 8, 1999·Veterinary Immunology and Immunopathology·T M Lian, R E Halliwell
Feb 8, 2003·The Veterinary Journal·U von RuedorfferM Welle
Sep 2, 2003·Journal of Feline Medicine and Surgery·G A KunkleD B Logas
Dec 12, 2012·Veterinary Immunology and Immunopathology·C MeulenbroeksT Willemse
May 1, 2004·The Journal of Small Animal Practice·M A FraserG Gettinby
May 12, 2004·Veterinary Immunology and Immunopathology·Melinda J WilkersonMichael Dryden
Nov 24, 1999·The Veterinary Clinics of North America. Small Animal Practice·D E Bevier
Nov 1, 1987·The Veterinary Clinics of North America. Small Animal Practice·K W Kwochka
Jan 1, 1987·The Veterinary Clinics of North America. Small Animal Practice·D W Scott, R T Horn
Jun 1, 1988·Journal of Veterinary Pharmacology and Therapeutics·J M YanniC H Tracy
Feb 11, 2012·The Journal of Veterinary Medical Science·Toshihiro TsukuiShigehiro Iwabuchi
Apr 9, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Huali JinBin Wang
Sep 26, 2014·PLoS Neglected Tropical Diseases·Christopher F BosioB Joseph Hinnebusch

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.