IgE level in newborn umbilical cord and its relationship with some maternal factors

Clinical and Molecular Allergy : CMA
Iraj MohammadzadehReza Alizadeh-Navaei

Abstract

Allergic diseases are among major pediatric issues as they are highly prevalent and chronic. Therefore, identification of factors contributing to allergic disease could play a significant role in prevention of these conditions. This study aimed at investigating the IgE level in newborn's umbilical cord blood and its relationship with some maternal factors. A cross-sectional study was conducted in 101 mothers and their newborns in Babol, Iran 2016. The samples were selected using non-probability convenience sampling. Information including newborn sex, gravidity, history of allergy before and during pregnancy (asthma, allergic rhinitis, eczema, hives, food allergy, and drug allergy), family history of allergy among mothers, history of exposure to secondhand smoke and pets, and delivery techniques was recorded. The IgE levels in newborn umbilical cord blood and maternal serum were measured using an IgE kit and ELISA technique. The newborns included 53 females (52.5%) and 29 mothers had vaginal birth (28.7%). History of exposure to secondhand smoke was found in 15 samples (14.9%), and 18 participants reported exposure to pets (17.8%). The median IgE levels in newborns and their mothers were 0.41 and 98.6, respectively. In general, ...Continue Reading

References

Aug 1, 1989·Archives of Disease in Childhood·R D CliffordS T Holgate
May 17, 2003·Current Opinion in Allergy and Clinical Immunology·Susan L Prescott
Jul 19, 2013·Asian Pacific Journal of Allergy and Immunology·Mohammad NabaviMohammad Faranoush
Sep 4, 2013·Allergy and Asthma Proceedings·Evelia HernándezIsabelle Romieu

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Citations

Jul 11, 2021·Environmental Science and Pollution Research International·Hosna JanjaniMasud Yunesian

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Methods Mentioned

BETA
ELISA
cesarean section

Software Mentioned

SPSS16

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