IgE-mediated allergy to corn: a 50 kDa protein, belonging to the Reduced Soluble Proteins, is a major allergen

Allergy
G PasiniM Giannattasio

Abstract

Although corn is often cited as an allergenic food, very few studies have been devoted to the identification of corn allergens and corn allergy has been rarely confirmed by double-blind, placebo-controlled food challenge (DBPCFC). Recently, Pastorello et al. (1) identified some salt-soluble IgE-binding proteins of corn flour as potential allergens. One of these, corresponding to corn Lipid Transfer Protein (LTP), appeared to be the major one. The aim of this study was to verify the clinical significance of the skin prick test (SPT) and CAP-FEIA CAP-System IgE fluozoenzyme immunosorbent assay (Pharmacia Diagnostic, Uppsala, Sweden) positivities to corn and to identify the presence of IgE-binding proteins in the corn flour salt-insoluble protein fractions (comprising up to 96% of the total protein) using sera of patients with DBPCFC-documented food allergy to corn. In addition the effect of cooking and proteolytic digestion on the corn allergens was investigated. Sixteen subjects with SPT and CAP-FEIA positivities to corn flour were examined. Only six of them complained of suffering from urticaria and/or other symptoms after ingestion of corn-based foods. The patients were food challenged with cooked corn flour (polenta). IgE-bin...Continue Reading

References

Dec 1, 1978·The Journal of Allergy and Clinical Immunology·S A BockC D May
Apr 1, 1990·The Biochemical Journal·P R Shewry, A S Tatham
Sep 1, 1995·The Journal of Allergy and Clinical Immunology·S M JonesH A Sampson
Jan 1, 1996·Critical Reviews in Food Science and Nutrition·S L Taylor, S B Lehrer
May 1, 1997·International Archives of Allergy and Immunology·S B Lehrer, G Reese
Jul 1, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H S Park, D H Nahm
Dec 31, 1997·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C P SandifordA J Newman Taylor
Oct 1, 1996·Nature Biotechnology·J D AstwoodR L Fuchs
Jul 2, 1998·The Journal of Allergy and Clinical Immunology·J D Pauls, D Cross
Sep 15, 1998·The Korean Journal of Internal Medicine·H S ParkK S Kim
Apr 15, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A CurioniM Giannattasio
Oct 14, 2000·The Journal of Allergy and Clinical Immunology·E A PastorelloC Ortolani
May 10, 2001·The Journal of Allergy and Clinical Immunology·S L Taylor, S L Hefle
Sep 12, 2001·Allergy·S G JohanssonUNKNOWN EAACI (the European Academy of Allergology and Cinical Immunology) nomenclature task force
Nov 7, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B SimonatoA Curioni

❮ Previous
Next ❯

Citations

Jan 17, 2009·Clinical and Molecular Allergy : CMA·Santiago Schnell, Rod A Herman
Jan 25, 2012·Journal of Proteomics·Cátia FonsecaRita Batista
Aug 22, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Richard E Goodman
May 31, 2007·The Australasian Journal of Dermatology·Wendy Liu, Rosemary L Nixon
Feb 26, 2010·Allergy·C-M ManiuN Hunzelmann
Dec 30, 2014·Journal of Agricultural and Food Chemistry·Severin E StevensonJay J Thelen
Oct 25, 2016·International Journal of Pharmaceutics·Yong ZhangWei Kong
Jun 20, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Matteo MarangonAndrea Curioni
Nov 15, 2008·Journal of Agricultural and Food Chemistry·Alberto FinamoreElena Mengheri
Jan 14, 2011·Journal of Agricultural and Food Chemistry·Hari B KrishnanHarold N Trick
Sep 30, 2005·Journal of Agricultural and Food Chemistry·Sung-Ho LeeBruce R Hamaker

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
C VenterT Dean
Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
H FrisnerV Barkholt
© 2022 Meta ULC. All rights reserved