PMID: 1087154Nov 11, 1976Paper

IgG antilymphocyte antibodies in SLE detected by 125I protein A

Arthritis and Rheumatism
R C WilliamsJ D Montaño

Abstract

125I-labeled protein A was utilized to detect lymphocyte binding of IgG at 37 degrees C in 50 sera from patients with SLE. IgG binding was partially inhibited by preincubation of test cells with immune complexes in 50% of sera. In 10%, cytophilic Ig was increased by immune complex preincubation, and in 40% no appreciable change was recorded. With purified preparations of T and B cells, binding of SLE IgG at 37 degrees C was equal for both cell populations.

References

Nov 1, 1975·The Journal of Clinical Investigation·G HusbyR C Williams
Feb 1, 1976·The Journal of Clinical Investigation·H G Bluestein, N J Zvaifler
Jan 1, 1976·The Journal of Clinical Investigation·A N TheofilopoulosF J Dixon
Mar 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·M L Tyan
Jun 1, 1975·The Journal of Clinical Investigation·R J DeHoratius, R P Messner
Jan 1, 1975·Scandinavian Journal of Immunology·I LindI Folling
Jul 1, 1972·The Journal of Experimental Medicine·H B Dickler, H G Kunkel
Apr 1, 1974·European Journal of Immunology·G Brown, M F Greaves
Jan 1, 1974·Scandinavian Journal of Immunology·G DorvalH Wigzell
Nov 1, 1974·Nature·R M LewisR S Schwartz
Dec 7, 1974·Lancet·B S OoiL Masaitis
Mar 1, 1970·Proceedings of the Society for Experimental Biology and Medicine·N Back, R Steger
Jul 1, 1970·The Journal of Experimental Medicine·B R BloomP I Marcus
Dec 19, 1974·The New England Journal of Medicine·C S Henney
Jul 1, 1973·The Journal of Experimental Medicine·D B Thomas, B Phillips
Dec 1, 1973·The Journal of Clinical Investigation·R P MessnerR C Williams
Sep 25, 1972·European Journal of Biochemistry·J SjöquistH Hjelm
Oct 1, 1970·The New England Journal of Medicine·P I TerasakiE V Barnett
Mar 28, 1970·Nature·K K MittalW T Butler

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Citations

Jun 1, 1978·Arthritis and Rheumatism·R C Williams, A D Bankhurst
Jun 1, 1978·Arthritis and Rheumatism·J B WinfieldA Singer
Jan 1, 1979·Arthritis and Rheumatism·M E Hamilton, J B Winfield
Mar 1, 1994·Clinical Rheumatology·C Osman, A J Swaak
Jan 1, 1977·Journal of Immunological Methods·J J LangoneT Borsos
Oct 1, 1977·The Journal of Clinical Investigation·S StagnoC A Alford
Feb 1, 1980·The Journal of Clinical Investigation·R C WilliamsM F Greaves
Sep 1, 1978·American Journal of Ophthalmology·D H CharP Stein
Oct 1, 1977·Kidney International·A J WoodroffeC B Wilson
Dec 1, 1987·Clinical Immunology and Immunopathology·B S EdwardsC L Hoffman
Dec 1, 1980·Clinical Immunology and Immunopathology·S H Packer, G L Logue

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