IgG heavy-chain (Gm) allotypes and immune response to insulin in insulin-requiring diabetes mellitus

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

IgG heavy-chain (Gm) allotypes and immune response to insulin in insulin-requiring diabetes mellitus

Abstract

References

Ir-gene control of immunogenicity of insulin and A-chain loop as a carrier determinant

Association between immunoglobulin allotypes and immune responses to Haemophilus influenzae and Meningococcus polysaccharides

Immune response gene control of determinant selection. I. Intramolecular mapping of the immunogenic sites on insulin recognized by guinea pig T and B cells

HLA antigens and immunoresponsiveness to insulin in insulin-dependent diabetes mellitus

The linkage relationships of HL-A with other genetic marker systems

Genetics of the antibody response to dextran in mice

HL-A, immune-response genes, and disease

Genetic control of specific immune responses

Nonprecipitating insulin antibodies

Citations

Interaction of HLA and immunoglobulin antigens in type 1 (insulin-dependent) diabetes

Genetic risk factors in diabetic retinopathy

A genetic study of retinopathy in south Indian type 2 (non-insulin-dependent) diabetic patients

The role of circulating immune complexes in the pathogenesis of diabetes mellitus

Gm allotype system and autoimmune diseases

Autoantibodies and immunoglobulin allotypes in healthy North American Blacks of different age groups

Graves' disease--the thyroid stimulating antibody and immunological networks

Immunological aspects of diabetes mellitus: prospects for pharmacological modification

Gm allotypes in blacks with systemic lupus erythematosus

Human immunoglobulin heavy-chain-variable (VH) region gene families defined by hybridization with cloned human and murine VH-genes

The contribution of non-MHC genes to susceptibility to autoimmune diseases

A reappraisal of rheumatic diseases and immunogenetics

Immunoglobulin allotypes Gm and Km in chronic schizophrenia: no apparent association

Human immunoglobulin allotypes: previously unrecognized determinants and alleles defined with monoclonal antibodies

Heterozygosity at Gm loci associated with humoral immunity to osteosarcoma

HLA-DR4 and Gm(1,3;5,21) are associated with U1-nRNP antibody positive connective tissue disease

Phenotypes of the heavy chains of immunoglobulins in patients with diabetic microangiopathy: evidence for an immunogenetic predisposition

Gluten-sensitive enteropathy. Immunoglobulin G heavy-chain (Gm) allotypes and the immune response to wheat gliadin

Susceptibility to multiple sclerosis associated with an immunoglobulin gamma 3 restriction fragment length polymorphism.

The genetics of diabetic complications

Immunoglobulin allotype markers and HLA DR genes in type I diabetes mellitus

Immunogenetics of early-onset insulin-dependent diabetes mellitus among the Japanese: HLA, Gm, BF, GLO, and organ-specific autoantibodies--the J.D.S. study

IgG heavy chain allotypes (Gm) in atrophic and goitrous thyroiditis

IgG and IgA heavy chain allotypes in Type 1 diabetes

Immunoglobulin (Gm) markers and alpha 1-antitrypsin (PI) types in rheumatoid arthritis and early onset chronic active hepatitis

Immunoglobulin allotypes in patients in end-stage renal failure

Lawrence lecture. Death of a beta cell: homicide or suicide?

Immunoglobulin heavy chain switch region polymorphisms are not associated with type 1 diabetes

Islet cell antibodies in diabetes

IgG heavy chain (Gm) allotypes in diabetes

The genetics of susceptibility to diabetes

Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32.3 producing susceptibility to type 1 diabetes

Two major genes, linked to HLA and Gm, control susceptibility to Graves' disease

Possible disorder of B-cell-related surveillance and malignant lymphoma of the thyroid.

No evidence for linkage between an insulin-dependent diabetes mellitus-susceptibility locus and immunoglobulin loci KM or GM

Complex segregation analysis for two-locus model: autosomal double recessive

Immunological responses to exogenous insulin

Immunoglobulin allotypes (GM and KM) and their interactions with HLA antigens in autoimmune diseases: a review

Interactive effect of HLA and Gm tested in a study of 135 juvenile insulin-dependent diabetic families

Autoimmunity, HLA, Gm and Km polymorphisms in Turner's syndrome

Coeliac disease: genetic, immunological and environmental factors in disease pathogenesis

Immunoglobulin allotypes and immunoglobulin G subclass responses to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in early-onset periodontitis.

IgG heavy-chain (Gm) allotypes in demyelinating polyneuropathy associated with MAG-binding monoclonal IgM autoantibodies

Relative Quantitation of Subclass-Specific Murine IgG Fc N -Glycoforms by Multiple Reaction Monitoring

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