PMID: 9205507May 1, 1997

IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes in patients with acne vulgaris

The British Journal of Dermatology
H Ruth AshbeeE Ingham

Abstract

IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes were determined in sera from patients with mild, moderate or severe acne and from a control group. Titres specific to S. epidermidis were all within the same range and did not differ between groups. The titres of IgG subclasses to specific to P. acnes did vary between groups. IgG1 and IgG3 were significantly higher in severe acne patients compared with moderate acne patients, while IgG2 was significantly higher in moderate and severe patients compared with controls. Titres of IgG4 did not differ between groups. The pattern of titres observed suggests that, while the antibody response to S. epidermidis is relatively harmless, antibodies to P. acnes may be involved in the pathogenesis of acne vulgaris.

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Citations

May 16, 2000·The British Journal of Dermatology·A E TillK T Holland
Mar 21, 2002·The British Journal of Dermatology·U JappeK T Holland
Jan 10, 2002·Clinical Microbiology Reviews·H Ruth Ashbee, E Glyn V Evans
Nov 22, 2011·Clinics in Plastic Surgery·Jean Krutmann
Feb 19, 2011·International Journal of Food Microbiology·Susana DelgadoBaltasar Mayo
Feb 11, 2009·Journal of Dermatological Science·Jean Krutmann
Sep 13, 2008·The Journal of Investigative Dermatology·Jenny Kim
Nov 25, 2003·Clinical and Experimental Immunology·K Dzierzanowska-FangratJ E Crabtree
Feb 16, 2006·Letters in Applied Microbiology·A L Perry, P A Lambert
Aug 3, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·C BeylotB Dreno
Mar 24, 2006·FEMS Microbiology Letters·M Marta GuarnaEvelina Rubinchik
Jul 2, 2014·Clinical Microbiology Reviews·Yvonne AchermannMark E Shirtliff

Related Concepts

Acne Vulgaris
Antibodies, Bacterial
Antibody Specificity
Polyglobin
Propionibacterium acnes
Staphylococcus epidermidis

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