PMID: 26819174Jan 29, 2016Paper

IgG4-related retroperitoneal fibrosis: A case report and review of literature

JPMA. the Journal of the Pakistan Medical Association
Azra NiazNauman Tarif

Abstract

Idiopathic Retroperitoneal fibrosis is a rare clinical condition recently identified as an autoimmune process related to Immunoglobulin G4 (IgG4) deposition. Herein we report a case of a 46 year old male presenting with 4 months history of backache, fever, flank pain and leg swelling for 2 weeks. Investigations revealed acute kidney injury diagnosed as a result of bilateral ureteric obstruction. This was later confirmed to be retroperitoneal fibrosis on CT scan and biopsy. Histopathology was consistent with IgG4 related disease. Treatment with immunosuppressive agents showed reduction in the fibrosis and normalization of the kidney functions. We discuss the IgG4 related retroperitoneal fibrosis in detail along with its varied presentations.

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
Wen-Hsiu WangWei-Sheng Chen
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
Satoko MaetaYoshikazu Murawaki
Hinyokika kiyo. Acta urologica Japonica
Tomohiko OguchiOsamu Muraishi
© 2021 Meta ULC. All rights reserved