IgG4-related systemic disease affecting the parotid and submandibular glands: magnetic resonance imaging features of IgG4-related chronic sclerosing sialadenitis and concomitant lymphadenitis

Clinical Imaging
Laurens J De CockerRobert Hermans

Abstract

IgG4-related systemic disease (IgG4-RSD) is a recently recognised fibroinflammatory condition, characterized by a tissue infiltration and/or enlargement and typical histopathological findings. We report on a 73-year-old male with bilateral preauricular swelling and a remote history of unexplained systemic disease. Magnetic resonance imaging showed enlargement of all major salivary glands and cervical lymph node due to a tissue infiltration with marked enhancement and restricted diffusion. Elevated serum IgG4 levels and histopathological findings on an excisional lymph node biopsy were consistent with IgG4-RSD. Magnetic resonance imaging seems to be a useful tool to support the diagnosis of IgG4-related systemic disease of salivary glands.

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Citations

Mar 24, 2015·The Journal of Laryngology and Otology·E L CulverP Martinez-Devesa
Jan 7, 2017·The Neuroradiology Journal·Ahmed Abdel Khalek Abdel Razek, Suresh Mukherji
Nov 8, 2017·Acta Clinica Belgica·Daniel Blockmans
Sep 28, 2018·La Radiologia medica·Manolya KaraAyper Somer
Sep 27, 2019·Ear, Nose, & Throat Journal·Joanna GodbehereSara Sionis

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