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IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment

Cancer Immunology, Immunotherapy : CII

Dec 6, 2019

Chunyan YuWeimin Deng

Abstract

Pro-inflammatory cytokines are crucial mediators of cancer development, representing potential targets for cancer therapy. The molecular mechanism of a vital pro-inflammatory cytokine, IL-17A, in cancer progression and its potential use in therapy through influencing fatty acid (FA) met...read more

Mentioned in this Paper

Study
In Vivo
Uptake
Neoplasms
IL17A
Cancer Progression
Short-chain Fatty Acid Import
Cell Proliferation
STAT3
Ovarian Carcinoma
1

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IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment

Cancer Immunology, Immunotherapy : CII

Dec 6, 2019

Chunyan YuWeimin Deng

PMID: 31802182

DOI: 10.1007/s00262-019-02445-2

Abstract

Pro-inflammatory cytokines are crucial mediators of cancer development, representing potential targets for cancer therapy. The molecular mechanism of a vital pro-inflammatory cytokine, IL-17A, in cancer progression and its potential use in therapy through influencing fatty acid (FA) met...read more

Mentioned in this Paper

Study
In Vivo
Uptake
Neoplasms
IL17A
Cancer Progression
Short-chain Fatty Acid Import
Cell Proliferation
STAT3
Ovarian Carcinoma
1

Similar Papers Found In These Feeds

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