ILM peeling in nontractional diabetic macular edema: review and metanalysis

International Ophthalmology
M RinaldiC Costagliola

Abstract

To evaluate the effect of internal limiting membrane (ILM) peeling during vitrectomy for nontractional diabetic macular edema. PUBMED, MEDLINE and CENTRAL were reviewed using the following terms (or combination of terms): diabetic macular edema, nontractional diabetic macular edema, internal limiting membrane peeling, vitrectomy, Müller cells. Randomized and nonrandomized studies were included. The eligible studies compared anatomical and functional outcomes of vitrectomy with or without ILM peeling for tractional and nontractional diabetic macular edema. Postoperative best-corrected visual acuity and central macular thickness were considered, respectively, the primary and secondary outcomes. Meta-analysis on mean differences between vitrectomy with and without ILM peeling was performed using inverse variance method in random effects. Four studies with 672 patients were eligible for analysis. No significant difference was found between postoperative best-corrected visual acuity or best-corrected visual acuity change of ILM peeling group compared with nonpeeling group. There was no significant difference in postoperative central macular thickness and central macular thickness reduction between the two groups. The visual acuity o...Continue Reading

References

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Sep 9, 2011·The British Journal of Ophthalmology·Laura TernentUNKNOWN Full-Thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS) Group
Apr 11, 2012·British Journal of Clinical Pharmacology·Michele RinaldiCiro Costagliola
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Citations

Oct 28, 2019·Ocular Immunology and Inflammation·Jeong Hun BaeQuan Dong Nguyen
Jul 31, 2019·Current Diabetes Reports·Eric J KimChristina Y Weng
Jul 6, 2020·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Alexander MehtaDavid H Steel

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