IM droperidol as premedication attenuates intraoperative hypothermia

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
K ToyotaT Matsukawa

Abstract

Perioperative hypothermia results largely from core-to-peripheral heat redistribution. Droperidol, which is often used for premedication, promotes vasodilation, and thus may affect redistribution of heat. Accordingly, we tested the hypothesis that preanesthetic droperidol would affect perioperative hypothermia. Twenty-three ASA physical status I patients scheduled for arthroscopic ligament reconstruction were randomly assigned to two groups to receive no premedication or im droperidol 0.1 mg x kg(-1) 30 min before anesthesia. Anesthesia was induced and maintained with propofol and fentanyl. We monitored core (tympanic) and peripheral (palm) temperatures, and skin (fingertip) blood flow for two hours after the induction of anesthesia during surgery. Before the induction of anesthesia, patients given droperidol were more deeply sedated than those given no premedication. Core temperature, which was similar in both groups before induction, decreased significantly more in the control than in the droperidol patients (0.75 +/- 0.34 degrees C and 0.37 +/- 0.20 degrees C, respectively, at 75 min after induction; P <0.01). Preinduction peripheral temperature and skin blood flow were lower in the control group than in the droperidol group...Continue Reading

References

Sep 1, 1988·Anesthesiology·D I SesslerE H Rubinstein
Aug 1, 1995·Anesthesia and Analgesia·A KurzA R Bjorksten
Mar 1, 1995·Anesthesiology·T MatsukawaC Cheng
Jan 1, 1994·Anesthesiology·N VassilieffA Lienhart
Apr 9, 1997·JAMA : the Journal of the American Medical Association·S M FrankC Beattie
Jan 7, 1998·Anesthesiology·R LenhardtF Lackner
May 29, 1998·British Journal of Anaesthesia·M BockJ Motsch
Jul 14, 1998·Anesthesia and Analgesia·J M BernardF Bonnet

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Citations

Dec 1, 2006·Der Anaesthesist·A BräuerM Quintel

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