Image-guided breast brachytherapy: an alternative to whole-breast radiotherapy

The Lancet Oncology
Rakesh R Patel, Rupak K Das

Abstract

Lumpectomy and whole-breast radiotherapy (ie, breast-conservation treatment) are accepted as viable alternatives to mastectomy in locoregional management of breast cancer. These techniques are used to keep morbidity to a minimum, optimise cosmesis, and maintain treatment outcomes. Pathological and clinical data suggest that most recurrences of cancer in the ipsilateral breast are in the vicinity of the index lesion, and that remote recurrences are uncommon, whether or not whole-breast radiotherapy is delivered. These data lend support to the idea of partial-breast radiotherapy. Such a restricted treatment volume allows safe delivery of an accelerated hypofractionated regimen over a shortened course of 1 week. This technique differs from that of standard whole-breast tangential external-beam radiotherapy and necessitates investigation of accelerated partial-breast irradiation (APBI). Several techniques of APBI are being investigated; however, most experience, and the most favourable early outcomes, has been obtained with image-guided breast brachytherapy. This review highlights the rationale and outcomes of brachytherapy techniques.

References

Mar 1, 1990·Cleveland Clinic Journal of Medicine·G Crile, C B Esselstyn
Jan 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Kathy L BaglanFrank A Vicini
Aug 21, 2003·Journal of the National Cancer Institute·Frank A ViciniAlvaro Martinez
Apr 6, 2004·Brachytherapy·Douglas W ArthurUNKNOWN American Brachytherapy Society
Jul 6, 2004·International Journal of Radiation Oncology, Biology, Physics·Rupak K DasRobert R Kuske
Mar 10, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Douglas W Arthur, Frank A Vicini

❮ Previous
Next ❯

Citations

Dec 17, 2008·Breast Cancer Research and Treatment·Antonio Llombart-Cussac
Sep 22, 2006·Current Opinion in Oncology·Erik Van Limbergen, Caroline Weltens
Apr 6, 2007·The Journal of the Acoustical Society of America·Jonathan Mamou, Ernest J Feleppa
Feb 2, 2012·International Journal of Breast Cancer·Jonathan WhiteMark Lansdown
Sep 23, 2011·Clinical Oncology : a Journal of the Royal College of Radiologists·J-P PignolW Hanna
Mar 8, 2011·Critical Reviews in Oncology/hematology·Christopher F NjehChristian M Langton
Aug 25, 2010·International Journal of Radiation Oncology, Biology, Physics·Derek R McHaffieGeorge M Cannon
Nov 27, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tibor MajorCsaba Polgár
Nov 27, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Cynthia AristeiPaolo Latini
Sep 15, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Abdel Kareem AzabAbraham Rubinstein
Aug 28, 2007·The Breast : Official Journal of the European Society of Mastology·R Orecchia, P Fossati
Feb 26, 2008·Medical Physics·Liyong LinDouglass L Henderson
Nov 24, 2018·Journal of Medical Imaging and Radiation Oncology·Boon H Chua, Tomas Kron

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.