Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage.

Surgical Neurology
Chad MillerNeil Martin

Abstract

Spontaneous ICH is a devastating disease with high morbidity and mortality. Intracerebral hemorrhage lacks an effective medical or surgical treatment despite the acknowledged pathophysiologic benefits of achieved hemostasis and clot removal. Image-guided stereotactic endoscopic hematoma evacuation is a promising minimally invasive approach designed to limit operative injury and maximize hematoma removal. A single-center randomized controlled trial was designed to assess the safety and efficacy of stereotactic hematoma evacuation compared to best medical management. Patients were randomized within 24 hours of hemorrhage in a 3:2 fashion to best medical management plus endoscopic hematoma evacuation or best medical management alone. Data were collected to assess efficacy and safety of hematoma evacuation and to identify procedural components requiring technical improvement. Ten patients have been enrolled and randomized to treatment. Six patients underwent endoscopic evacuation with a hematoma volume reduction of 80% +/- 13% at 24 hours post procedure. The medical arm demonstrated a hematoma enlargement of 78% +/- 142% during this same period. Rehemorrhage rates and deterioration rates were similar in the 2 groups. Mortality was ...Continue Reading

References

Jan 1, 1990·Stroke; a Journal of Cerebral Circulation·S KojimaY Komachi
Nov 1, 1984·Stroke; a Journal of Cerebral Circulation·S Helweg-LarsenG Boysen
Jul 1, 1982·Stroke; a Journal of Cerebral Circulation·M A Douglas, A F Haerer
Dec 19, 2002·Neurosurgery Clinics of North America·Guohua XiJulian T Hoff
Nov 15, 2003·Stroke; a Journal of Cerebral Circulation·Jimin WuGuohua Xi
Dec 4, 2004·Minimally Invasive Neurosurgery : MIN·M N Carvi y NievasE Archavlis

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Citations

Oct 29, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Mahesh Ramanan, Aparna Shankar
Jan 12, 2011·Current Treatment Options in Neurology·Joshua N Goldstein, Aaron J Gilson
Nov 30, 2013·Neurologic Clinics·Paul M Vespa
Dec 17, 2011·Lancet Neurology·Joyce S Balami, Alastair M Buchan
Sep 16, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Guofeng WuGuannan Qin
May 8, 2015·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Damon KlebeJiping Tang
Dec 21, 2013·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Justin A DyeHarry V Vinters
May 8, 2013·IEEE Transactions on Bio-medical Engineering·Jessica BurgnerRobert J Webster
Aug 5, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Colin J PrzybylowskiKenneth C Liu
Feb 18, 2015·Neurosurgical Review·Christopher BeynonBerk Orakcioglu
Jul 28, 2016·World Neurosurgery·YuanZheng HouXiaoLei Chen
Aug 22, 2016·World Neurosurgery·Zhibo GaoXianming Fu
Aug 19, 2017·Neurologia Medico-chirurgica·Motohiro Morioka, Kimihiko Orito
Apr 29, 2010·Neurorehabilitation and Neural Repair·Jin ZhongS Thomas Carmichael
Mar 17, 2009·Stroke; a Journal of Cerebral Circulation·Paul M Vespa
Aug 31, 2018·Journal of Neurosurgical Sciences·Claudio CavalloPeter Nakaji
Sep 30, 2010·Nature Reviews. Neurology·Opeolu Adeoye, Joseph P Broderick
Apr 3, 2020·Annals of Neurology·Lotte SondagUNKNOWN Dutch ICH Surgery Trial Study Group, part of the CONTRAST consortium†
Oct 26, 2018·Stroke; a Journal of Cerebral Circulation·Jacopo ScaggianteChristopher P Kellner
Jun 3, 2021·International Journal of Molecular Sciences·Jesse A StokumJ Marc Simard

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