Image-guided stereotactic body radiotherapy for lung tumors using BodyLoc with tomotherapy: clinical implementation and set-up accuracy

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Jining ZhouYeh-Chi Lo

Abstract

We investigated the use of a BodyLoc immobilization and stereotactic localization device combined with TomoTherapy megavoltage CT (MVCT) in lung stereotactic body radiotherapy (SBRT) to reduce set-up uncertainty and treatment time. Eight patients treated with 3-5 fractions of SBRT were retrospectively analyzed. A BodyLoc localizer was used in both CT simulation for localization and the initial patient treatment set-up. Patients were immobilized with a vacuum cushion on the back and a thermoplastic body cast on the anterior body. Pretreatment MVCT from the TomoTherapy unit was fused with the planning kilovoltage CT (KVCT) before each fraction of treatment to determine interfractional set-up error. The comparison of two MVCTs during a fraction of treatment resulted in the intrafractional uncertainty of the treatment. A total of 224 target isocenter shifts were analyzed to assess these inter- and intrafractional tumor motions. We found that for interfractional shifts, the mean set-up errors and standard deviations were -1.1 +/- 2.8 mm, -2.5 +/- 8.7 mm, and 4.1 +/- 2.6 mm, for lateral, longitudinal, and vertical variation, respectively; the mean setup rotational variation was -0.3 +/- 0.7 degrees; and the maximum motion was 13.5 mm...Continue Reading

References

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Citations

May 4, 2010·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Alonso N GutiérrezNiko Papanikolaou
Mar 1, 2012·International Journal of Radiation Oncology, Biology, Physics·Chin Loon OngSuresh Senan
Apr 9, 2014·Journal of Applied Clinical Medical Physics·Young-Kee OhJin-Hee Kim
Apr 9, 2014·Journal of Applied Clinical Medical Physics·Travis C Greene, X John Rong
May 16, 2017·Journal of Applied Clinical Medical Physics·Yoshihiro UedaIndra J Das
Jul 7, 2011·Technology in Cancer Research & Treatment·Wensha YangKe Sheng
Jul 18, 2021·Journal of Applied Clinical Medical Physics·Geoffrey BaranJay W Burmeister

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