Image quality and detectability in Siemens Biograph PET/MRI and PET/CT systems-a phantom study

EJNMMI Physics
Silje Kjærnes ØenAnna M Karlberg

Abstract

The technology of modern positron emission tomography (PET) systems continuously improving, and with it the possibility to detect smaller lesions. Since first introduced in 2010, the number of hybrid PET/magnetic resonance imaging (MRI) systems worldwide is constantly increasing. It is therefore important to assess and compare the image quality, in terms of detectability, between the PET/MRI and the well-established PET/computed tomography (CT) systems. For this purpose, a PET image quality phantom (Esser) with hot spheres, ranging from 4 to 20 mm in diameter, was prepared with fluorodeoxyglucose and sphere-to-background activity concentrations of 8:1 and 4:1, to mimic clinical conditions. The phantom was scanned on a PET/MRI and a PET/CT system for both concentrations to obtain contrast recovery coefficients (CRCs) and contrast-to-noise ratios (CNRs), for a range of reconstruction settings. The detectability of the spheres was scored by three human observers for both systems and concentrations and all reconstructions. Furthermore, the impact of acquisition time on CNR and observer detectability was investigated. Reconstructions applying point-spread-function modeling (and time-of-flight for the PET/CT) yielded the highest CRC ...Continue Reading

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Citations

Jan 15, 2020·EJNMMI Physics·Pablo García-Pérez, Samuel España
Oct 15, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Vanessa NadigVolkmar Schulz

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