Image reconstruction for dynamic PET based on low-order approximation and restoration of the sinogram

IEEE Transactions on Medical Imaging
C M KaoM N Wernick

Abstract

Many image-reconstruction methods have been proposed to improve the spatial resolution of positron emission tomography (PET) images and, thus, to produce better quantification. However, these techniques, which are designed for static images, may be inadequate for good reconstruction from dynamic data. We present a simple, but effective, reconstruction approach intended specifically for dynamic studies. First, the level of noise in dynamic PET data is reduced by smoothing along the time axis using a low-order approximation. Next, the denoised sinograms are restored spatially by the method of projections onto convex sets. Finally, images are reconstructed from the restored sinograms by ordinary filtered backprojection. We present experimental results that demonstrate substantial improvements in region-of-interest quantification in actual and simulated dopamine D-2 neuroreceptor-imaging studies of a monkey brain.

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Citations

Mar 29, 2011·Physics in Medicine and Biology·S TongP Shi
Jun 18, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Bradley T ChristianCharles A Mistretta
Dec 17, 2010·Medical Physics·Peter ForthmannPatrick La Riviere
Feb 13, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gage RedlerHoward J Halpern
Aug 6, 2014·IEEE Transactions on Medical Imaging·Guobao Wang, Jinyi Qi
Aug 10, 2006·IEEE Transactions on Medical Imaging·Patrick J La RivièrePhillip A Vargas
May 14, 2005·IEEE Transactions on Medical Imaging·M E KamasakK Sauer
Aug 23, 2012·IEEE Transactions on Medical Imaging·Xin LiuJing Bai
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Mar 10, 2005·IEEE Transactions on Medical Imaging·Jeong-Won JeongVasilis Z Marmarelis
Jun 25, 2016·Journal of X-ray Science and Technology·Yuanyuan GaoWufan Chen
May 30, 2008·International Journal of Image and Graphics·Yi FanZhiming Zhou
Nov 4, 2005·Medical Physics·Jovan G BrankovMiles N Wernick
Feb 3, 2015·Journal of Medical Imaging·Dimple ModgilPatrick J La Rivière
Apr 7, 2007·Neuroreport·Janniko R GeorgiadisRudie Kortekaas
Jul 28, 2016·Physics in Medicine and Biology·Zheng ZhangXiaochuan Pan

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