PMID: 8348907Jun 1, 1993

Image segmentation: methods and applications in diagnostic radiology and nuclear medicine

European Journal of Radiology
P SuetensL Mortelmans


We review and discuss different classes of image segmentation methods. The usefulness of these methods is illustrated by a number of clinical cases. Segmentation is the process of assigning labels to pixels in 2D images or voxels in 3D images. Typically the effect is that the image is split up into segments, also called regions or areas. In medical imaging it is essential for quantification of outlined structures and for 3D visualization of relevant image data. Based on the level of implemented model knowledge we have classified these methods into (1) manual delineation, (2) low-level segmentation, and (3) model-based segmentation. Pure manual delineation of structures in a series of images is time-consuming and user-dependent and should therefore be restricted to quick experiments. Low-level segmentation analyzes the image locally at each pixel in the image and is practically limited to high-contrast images. Model-based segmentation uses knowledge of object structure such as global shape or semantic context. It typically requires an initialization, for example in the form of a rough approximation of the contour to be found. In practice it turns out that the use of high-level knowledge, e.g. anatomical knowledge, in the segment...Continue Reading


Jan 1, 1990·International Journal of Cardiac Imaging·C SmetsA Oosterlinck
Jan 1, 1991·IEEE Transactions on Medical Imaging·J NuytsL Mortelmans


Sep 25, 1998·Medical & Biological Engineering & Computing·T HeinonenH Eskola
Mar 15, 2013·Computers in Biology and Medicine·D Salas-GonzálezA Ortiz
May 1, 1997·Computer Methods and Programs in Biomedicine·P A FreeboroughR I Kitney
Jul 16, 2010·BMC Musculoskeletal Disorders·Martijn RaaijmaakersMichiel Mulier
Aug 13, 2015·Artificial Intelligence in Medicine·Niels PeekRiccardo Bellazzi
Apr 8, 1999·IEEE Transactions on Medical Imaging·N ShareefR Yagel
Aug 19, 2016·Biomedical Engineering Online·Robert Koprowski, Paweł Olczyk
Jun 6, 1998·Otolaryngologic Clinics of North America·G J WietD J Sessanna
Jul 28, 2009·Analytical and Bioanalytical Chemistry·Leonardo C Pacheco-LondoñoSamuel P Hernández-Rivera
Nov 26, 2009·Annals of Biomedical Engineering·Jia-Xiu LiuLi-Fen Chen
Jan 1, 1996·Acta Oncologica·K SjörgreenS E Strand

Related Concepts

Computer Graphics
Optical Image Reconstruction
Magnetization Transfer Contrast Imaging
Picture Archiving and Communication Systems
Tomography, Emission-Computed
Virtual Systems
Tomography, Emission-Computed, Single-Photon

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Related Papers

Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
G T Herman
Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
N TomuraM Kowada
© 2021 Meta ULC. All rights reserved