PMID: 15220726Jun 29, 2004Paper

Imaging and quantification of calcified corneal lesions with optical coherence tomography

Cornea
Christopher Wirbelauer, Duy Thoai Pham

Abstract

The purpose of this study was to image and quantify calcified corneal lesions with optical coherence tomography (OCT) and to evaluate this diagnostic method to assess this corneal disease. In a clinical study 15 eyes of 14 patients with calcified corneal lesions in the anterior portions of the cornea were assessed with slit-lamp biomicroscopy and slit-lamp-adapted OCT. The qualitative and quantitative optical changes were compared with the clinical findings. In corneal OCT all calcified lesions revealed marked hyperreflective changes that correlated well with macroscopic findings. Dense calcified lesions resulted in partial or complete shadowing of the posterior corneal structures. The thickness values for the hyperreflective calcified lesions ranged from 27 to 344 microm. Noncontact slit-lamp-adapted OCT may be of value in assessing calcified corneal lesions. Corneal OCT could also be used to precisely measure the depth of these corneal processes and evaluate treatment modalities.

References

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Oct 12, 2001·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C WirbelauerD T Pham
Jan 22, 2002·The British Journal of Ophthalmology·K K NischalD S Rootman
Apr 5, 2002·American Journal of Ophthalmology·Christopher WirbelauerReginald Birngruber
Sep 17, 2002·Journal of Cataract and Refractive Surgery·Christopher WirbelauerDuy Thoai Pham
Sep 25, 2002·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christopher WirbelauerDuy Thoai Pham

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Citations

May 3, 2005·Lasers in Medical Science·F D VerbraakT G van Leeuwen
Nov 15, 2006·Cornea·Bartłomiej J KaluznyPiotr Targowski
Sep 11, 2008·The Ocular Surface·Trefford Simpson, Desmond Fonn
Mar 6, 2008·Ophthalmology·Christopher Wirbelauer
Nov 22, 2007·American Journal of Ophthalmology·Laurence S LimDonald T H Tan
Feb 27, 2007·Journal of Cataract and Refractive Surgery·Gregor WollensakChristopher Wirbelauer
Apr 9, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·M NilssonR L Brautaset
Apr 25, 2018·BMC Ophthalmology·Yi-Ju HoHung-Chi Chen
Dec 7, 2007·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Harsha S ReddyDavid Huang

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