Imaging Atherosclerosis.

Circulation Research
Jason M TarkinJames H F Rudd

Abstract

Advances in atherosclerosis imaging technology and research have provided a range of diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular imaging methods additionally promise great scientific and translational applications beyond this quest. When combined with conventional anatomic- and hemodynamic-based assessments of disease severity, cross-sectional multimodal imaging incorporating molecular probes and other novel noninvasive techniques can add detailed interrogation of plaque composition, activity, and overall disease burden. In the catheterization laboratory, intravascular imaging provides unparalleled access to the world beneath the plaque surface, allowing tissue characterization and measurement of cap thickness with micrometer spatial resolution. Atherosclerosis imaging captures key data that reveal snapshots into underlying biology, which can test our understanding of fundamental research questions and shape our approach toward patient management. Imaging can also be used to quantify response to therapeutic interventions and ultimately help predict cardiovascular risk. Although there are undeniable barriers to clinical translation, many of these hold-ups might soon be surpassed b...Continue Reading

References

Jan 5, 2002·The New England Journal of Medicine·W Y KimW J Manning
Sep 25, 2002·Circulation·Hiroshi YabushitaGuillermo J Tearney
Mar 5, 2004·JAMA : the Journal of the American Medical Association·Steven E NissenUNKNOWN REVERSAL Investigators
Jul 23, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Renu VirmaniJagat Narula
Mar 15, 2006·JAMA : the Journal of the American Medical Association·Steven E NissenUNKNOWN ASTEROID Investigators
Mar 24, 2006·Journal of Magnetic Resonance Imaging : JMRI·Vasily L YarnykhChun Yuan
Apr 22, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Rikin A TrivediJonathan H Gillard
Apr 25, 2006·Journal of the American College of Cardiology·Renu VirmaniFrank D Kolodgie
Apr 25, 2006·Journal of the American College of Cardiology·Jay D CaplanJames E Muller
Sep 26, 2006·American Heart Journal·Teruyoshi KumeKiyoshi Yoshida
Nov 7, 2006·Journal of the American College of Cardiology·Nobuhiro TaharaTsutomu Imaizumi
Nov 23, 2006·Journal of the American College of Cardiology·Hajime SakumaKan Takeda
Mar 27, 2007·JAMA : the Journal of the American Medical Association·John R CrouseUNKNOWN METEOR Study Group
Mar 28, 2007·The New England Journal of Medicine·William E BodenUNKNOWN COURAGE Trial Research Group
Sep 4, 2007·Journal of the American College of Cardiology·Pavan K CheruvuJames E Muller
Oct 9, 2007·Journal of Vascular Surgery·Luciano Cabral AlbuquerqueLuis Eduardo Rohde
Oct 27, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Martina A McAteerRobin P Choudhury
Mar 28, 2008·The New England Journal of Medicine·Robert DetranoRichard A Kronmal
May 17, 2008·Nature Reviews. Drug Discovery·Alistair C Lindsay, Robin P Choudhury
Sep 18, 2008·Radiology·Richard BitarRobert Maggisano
Oct 16, 2008·JAMA : the Journal of the American Medical Association·Grace A LinRita F Redberg
Nov 29, 2008·The New England Journal of Medicine·Julie M MillerJoão A C Lima
Dec 20, 2008·Journal of the American College of Cardiology·W Bob MeijboomPim J de Feyter
Mar 18, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Joanna WykrzykowskaRoger Laham
Jun 9, 2009·The New England Journal of Medicine·UNKNOWN BARI 2D Study GroupBurton E Sobel
Jun 10, 2009·Nature Reviews. Cardiology·Jonathan R Lindner
Jun 27, 2009·Journal of the American College of Cardiology·Sadako MotoyamaJagat Narula
Mar 12, 2010·The New England Journal of Medicine·Manesh R PatelPamela S Douglas

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Citations

Jun 29, 2016·Atherosclerosis·Osman Najam, Kausik K Ray
Jul 13, 2016·Atherosclerosis·Nikolaos TsigkasYiannis S Chatzizisis
Sep 24, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Markus SchwaigerStephan G Nekolla
Dec 25, 2016·European Heart Journal Cardiovascular Imaging·Konstantinos ToutouzasConstantinos D Anagnostopoulos
Feb 17, 2017·The FEBS Journal·Tommy Weiss-SadanGalia Blum
Jan 12, 2017·The International Journal of Cardiovascular Imaging·Parham EshtehardiHabib Samady
May 31, 2017·Nature Biomedical Engineering·Luis E SavastanoThomas D Wang
Nov 15, 2017·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Hui LiuZhude Tu
Nov 22, 2017·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Guan WangPaul A Bottomley
Oct 27, 2017·Arteriosclerosis, Thrombosis, and Vascular Biology·Eva ZupančičWillem J M Mulder
Feb 21, 2019·Journal of Biomedical Optics·Parker WrayLihong V Wang
Mar 9, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yongjian Liu, Pamela K Woodard
Sep 1, 2019·Current Pharmaceutical Design·Luca Liberale, Giovanni G Camici
Jan 28, 2020·Annual Review of Medicine·Ira J GoldbergEdward A Fisher
Dec 18, 2019·Heart·Neil Ruparelia, Robin Choudhury
Sep 30, 2016·Annals of Medicine·Cesare R SirtoriRebecca Perry
Mar 31, 2018·Frontiers in Immunology·Yue Li, Tzu-Ming Liu
Jan 22, 2019·Science Advances·Xiaoqiu XuJianxiang Zhang
Jul 22, 2018·The International Journal of Cardiovascular Imaging·Masafumi KidohYasuyuki Yamashita
Oct 26, 2018·Circulation. Cardiovascular Imaging·Raphaël Duivenvoorden, Willem J M Mulder
May 10, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Wenjin LiuChun Yuan
Sep 13, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Evangelos K OikonomouCharalambos Antoniades
Feb 23, 2020·The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica·Gyu S HeoYongjian Liu
Nov 18, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Olivia SorciChamith S Rajapakse
Sep 5, 2020·International Journal of Nanomedicine·Mona AhmedKenneth Caidahl
Jul 30, 2016·Current Opinion in Lipidology·Margreet R de Vries, Paul H A Quax
Nov 18, 2018·Journal of Nanobiotechnology·Christopher PoonEun Ji Chung
Dec 6, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Max KiugelAnne Roivainen
Apr 21, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Xiang LiMarcus Hacker
Sep 11, 2019·The British Journal of Radiology·Maaz Bj SyedEdwin Jr van Beek
May 6, 2020·European Heart Journal Supplements : Journal of the European Society of Cardiology·Tobias LenzMichael Joner
Jun 6, 2018·Frontiers in Cardiovascular Medicine·Karishma Rahman, Edward A Fisher

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Methods Mentioned

BETA
X-ray
imaging technique
x-ray fluoroscopy
coronary artery bypass
electron microscopy
Fluorescence
Percutaneous Coronary Intervention
imaging techniques

Clinical Trials Mentioned

NCT01471522
NCT02110303
NCT02278211
NCT01327846

Software Mentioned

BioImage
PROSPECT

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