Imaging developmental cell cycles.

Biophysical Journal
Abraham Q KohrmanEszter Posfai

Abstract

The last decade has seen a major expansion in development of live biosensors, the tools needed to genetically encode them into model organisms, and the microscopic techniques used to visualize them. When combined, these offer us powerful tools with which to make fundamental discoveries about complex biological processes. In this review, we summarize the availability of biosensors to visualize an essential cellular process, the cell cycle, and the techniques for single-cell tracking and quantification of these reporters. We also highlight studies investigating the connection of cellular behavior to the cell cycle, particularly through live imaging, and anticipate exciting discoveries with the combination of these technologies in developmental contexts.

References

Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·A B Pardee
Nov 1, 1983·Developmental Biology·J E SulstonJ N Thomson
Jan 1, 1983·The Journal of Cell Biology·W C Earnshaw, U K Laemmli
Dec 1, 1996·Current Biology : CB·S J Taylor, D Shalloway
Oct 9, 1998·Journal of Neuroscience Methods·J Muthuswamy, N V Thakor
Aug 23, 2001·Journal of Biomedical Optics·A Periasamy
Dec 3, 2002·Gene·Olivier Coqueret
Mar 13, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Stephen Cooper
Apr 14, 2004·Genes & Development·Arnaud BessonJames M Roberts
Feb 16, 2006·Proceedings of the National Academy of Sciences of the United States of America·Zhirong BaoRobert H Waterston
Apr 5, 2007·Nature Protocols·John Isaac MurrayRobert H Waterston
Nov 24, 2007·Current Opinion in Cell Biology·Laura A Buttitta, Bruce A Edgar
Feb 13, 2008·Cell·Asako Sakaue-SawanoAtsushi Miyawaki
Mar 12, 2008·Developmental Cell·Ian A Swinburne, Pamela A Silver
Jun 24, 2008·Nature Reviews. Molecular Cell Biology·Dieter EgliKevin Eggan
Aug 16, 2008·Genes & Development·Ian A SwinburnePamela A Silver
Apr 24, 2010·Developmental Cell·Olivier Gavet, Jonathon Pines
Mar 6, 2012·Developmental Biology·Dennis A RidenourPaul M Kulesa
Jun 30, 2012·Nature Methods·Johannes SchindelinAlbert Cardona
Nov 28, 2012·Stem Cell Research·Diana CoronadoPierre Savatier
Nov 30, 2012·Development·Marta RoccioMatthias P Lutolf
May 24, 2013·Nature Reviews. Molecular Cell Biology·Tom H Cheung, Thomas A Rando
Aug 13, 2013·PLoS Computational Biology·C J ZopfNarendra Maheshri
Oct 1, 2013·Cell·Siim Pauklin, Ludovic Vallier
Oct 22, 2013·Nature Methods·Martin Krzywinski, Naomi Altman
Oct 25, 2013·Development·Asako Sakaue-SawanoAtsushi Miyawaki

❮ Previous
Next ❯

Citations

Jun 25, 2021·Development·Susanna E Brantley, Stefano Di Talia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Cell & Developmental Biology
Frank Davis, Séamus P J Higson
IEEE Transactions on Bio-medical Engineering
ASAIO Transactions
W H Ko
Journal of Biotechnology
F Scheller
Current Opinion in Biotechnology
G G Guilbault
© 2021 Meta ULC. All rights reserved