Imaging features of atypical thoracic Castleman disease

Clinical Imaging
Sheung-Fat KoWei-Jen Chen

Abstract

The imaging features of 16 cases of pathologically proven atypical thoracic Castleman disease (CD) were retrospectively reviewed. Thirteen out of 16 tumors originated from atypical locations, including eight from the pleura and one each from the axilla, supraclavicular fossa, intercostal space, pericardium, and lung. Six out of 16 tumors revealed atypical enhancement, including poor CT enhancement in three tumors, target-like CT enhancement in two tumors, and concentric MR enhancement pattern in one tumor. These atypical enhancement patterns were histopathologically corresponded to various degrees of degeneration, necrosis, and fibrosis.

References

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Citations

Oct 22, 2011·Italian Journal of Pediatrics·Piero FarruggiaPaolo D'Angelo
Apr 16, 2008·Srpski arhiv za celokupno lekarstvo·Jelena StojsićJelena Radojicić
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Jun 27, 2020·Seminars in Diagnostic Pathology·Ha Nguyen, Joo Y Song

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Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.