Imaging findings of familial Mediterranean fever

Clinical Imaging
Gisele E IshakMaurice C Haddad

Abstract

The aim of this study was to study the imaging findings of familial Mediterranean fever (FMF). We performed a retrospective review of the medical records and imaging studies of 38 patients with proven FMF, diagnosed between 1992 and 2002. The most common clinical manifestation was recurrent peritoneal attacks with abdominal pain (76.3%) and fever (42.1%). Abdominal imaging findings included ileus (n=12), splenomegaly (n=5), hepatomegaly (n=2), ascitis (n=2), focal peritonitis (n=2), mesenteric streaking (n=1), and enlarged mesenteric lymph node (n=1). One patient developed fatal peritoneal mesothelioma, and 13.1% of the patients developed amyloidosis with sonographic findings of renal parenchymal disease or cardiomyopathy. Arthritis was second in frequency, occurring in 34.2% of patients; radiographs were normal (n=4) or showed joint effusion and periarticular soft tissue swelling (n=4) due to synovitis. One patient developed seronegative destructive arthropathy. Skin lesions were noted in 23.6% of patients. Pleuritis was encountered in 13.1% and pericarditis in 5.2%. Polyarteritis nodosa (PAN) was present in two patients, multiple sclerosis in one, and autoimmune hemolytic anemia in one patient. FMF predominantly involves abdo...Continue Reading

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Citations

Jan 25, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Yuen Yee ChengGlen Reid
Sep 24, 2008·Revue neurologique·A GuinetF Pico
Mar 18, 2011·Journal of Cellular Physiology·Michele CarboneHaining Yang
Nov 5, 2016·Annals of the Rheumatic Diseases·Nienke M Ter HaarJoost Frenkel
Feb 18, 2020·Pediatric Radiology·María NavallasOscar M Navarro

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