Imaging in vivo secondary caries and ex vivo dental biofilms using cross-polarization optical coherence tomography.

Dental Materials : Official Publication of the Academy of Dental Materials
Pat LentonR S Jones

Abstract

Conventional diagnostic methods frequently detect only late stage enamel demineralization under composite resin restorations. The objective of this study is to examine the subsurface tooth-composite interface and to assess for the presence of secondary caries in pediatric patients using a novel Optical Coherence Tomography System with an intraoral probe. A newly designed intraoral cross polarization swept source optical coherence tomography (CP-OCT) imaging system was used to examine the integrity of the enamel-composite interfaces in vivo. Twenty-two pediatric subjects were recruited with either recently placed or long standing composite restorations in their primary teeth. To better understand how bacterial biofilms cause demineralization at the interface, we also used the intraoral CP-OCT system to assess ex vivo bacterial biofilm growth on dental composites. As a positive control, cavitated secondary carious interfaces showed a 18.2dB increase (p<0.001), or over 1-2 orders of magnitude higher, scattering than interfaces associated with recently placed composite restorations. Several long standing composite restorations, which appeared clinically sound, had a marked increase in scattering than recently placed restorations. T...Continue Reading

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Citations

Dec 12, 2012·Journal of Biomedical Optics·Carmen LammeierRobert S Jones
Mar 30, 2013·BMC Oral Health·Zachary Van Hilsen, Robert S Jones
Feb 16, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Jacob C SimonDaniel Fried
Jan 1, 2013·Pathogens·David LebeauxChristophe Beloin
Mar 10, 2015·Dental Materials Journal·Ehab Z AlsayedJunji Tagami
Jul 15, 2015·Biotechnology and Bioengineering·Karin RasmussenRobert S Jones
Sep 29, 2015·Lasers in Surgery and Medicine·Jennifer S HoltzmanPetra Wilder-Smith
Jun 12, 2014·Lasers in Surgery and Medicine·Janet AjdaharianPetra Wilder-Smith
Oct 10, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Darren M IsfeldRobert S Jones
Apr 15, 2014·Lasers in Surgery and Medicine·Jennifer S HoltzmanPetra Wilder-Smith
Mar 22, 2016·Lasers in Surgery and Medicine·Stephanie MansourPetra Wilder-Smith
Apr 17, 2015·Journal of Periodontology·Cláudia C B O MotaAnderson S L Gomes
Mar 3, 2015·The Review of Scientific Instruments·Linsheng LiuKazuhiro Nonaka
Jul 19, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Kei HorieJunji Tagami
Aug 25, 2016·Journal of Applied Oral Science : Revista FOB·Ayşe Gözde TürkMübin Ulusoy
Aug 24, 2018·Dental Materials Journal·Anna Sipe, Robert S Jones
Jun 5, 2019·Journal of Clinical Medicine·Keunbada SonByoung-Ju Yun
Apr 6, 2018·Clinical Microbiology Reviews·Maria MaganaGeorge P Tegos
May 31, 2018·Photomedicine and Laser Surgery·Alaa TurkistaniTurki Bakhsh
Aug 29, 2014·Journal of Biomedical Optics·Gerd KeiserPerry Ping Shum
Jun 27, 2015·Biomedical Optics Express·Jason M Tucker-SchwartzMelissa C Skala
May 5, 2018·Lasers in Medical Science·Kyung-Jin ParkRainer Haak
May 16, 2019·Photobiomodulation, Photomedicine, and Laser Surgery·Turki A BakhshAhmad O Jamleh
Nov 15, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andrea LockeAnita Mahadevan-Jansen
May 10, 2021·Dental Materials : Official Publication of the Academy of Dental Materials·Yuan ZhouXiping Feng
May 29, 2021·Microscopy Research and Technique·Raquel Viana RodriguesFernanda Miori Pascon

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