Imaging of acute and subacute toxicities of cancer therapy in children

Pediatric Radiology
Govind B ChavhanSue C Kaste

Abstract

Effective cancer therapies have resulted in significant improvement in survival. However, treatment-related acute and subacute complications are a cause of significant morbidity and mortality. Effects of cancer therapy in children can be seen early in the survival period or later in life in almost all organ systems of the body. Many of these conditions are evaluated by imaging and some are diagnosed based on characteristic imaging features. This article aims to discuss acute and subacute toxicities of cancer therapy in children involving multiple organ systems, pulmonary, gastrointestinal, hepatobiliary, genitourinary and musculoskeletal systems with emphasis on those in which imaging plays a role in diagnosis or management. We also discuss the role of imaging and choice of imaging modalities in these conditions.

References

Aug 1, 1979·International Journal of Radiation Oncology, Biology, Physics·J L RansomC B Pratt
Apr 1, 1996·Radiology·L F Donnelly, C L Morris
Aug 18, 1997·Pediatric Radiology·B D Fletcher
Feb 7, 2001·Pediatric Radiology·M B McCarvilleJ J Jenkins
May 3, 2000·Alimentary Pharmacology & Therapeutics·W K MacNaughton
Feb 13, 2001·British Journal of Haematology·D R HargraveUNKNOWN Medical Research Council Working Party for Childhood Leukaemia
Feb 24, 2001·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·P CzaudernaJ Godziński
Apr 3, 2002·Seminars in Liver Disease·Laurie D DeLeveGeorge B McDonald
Oct 30, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ursula CreutzigThomas Lehrnbecher
Apr 26, 2005·Acta Oncologica·Luis Felipe Fajardo
Jun 14, 2005·Cancer·M Beth McCarvilleJohn T Sandlund
Jan 21, 2006·AJR. American Journal of Roentgenology·Evguenia J KarimovaSue C Kaste
Mar 22, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Daniel S LevineSusan I Blaser
May 22, 2007·Pediatric Blood & Cancer·Christoph HärtelChristian Schultz
Jun 28, 2007·JAMA : the Journal of the American Medical Association·Maud M GeenenFlora E van Leeuwen
Jul 24, 2008·Bone Marrow Transplantation·M MianoUNKNOWN EBMT Paediatric Working Party
Jul 22, 2008·Radiology·Caroline L HollingsworthVinod K Prasad
Feb 25, 2009·European Radiology·Philip J A Robinson
Mar 14, 2009·Advances in Experimental Medicine and Biology·Stéphane Paulus, Simon Dobson
Jul 17, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Amir A BorhaniMichael Nalesnik
Aug 1, 2009·Journal of Pediatric Hematology/oncology·Hana HakimAditya H Gaur
Oct 20, 2010·British Journal of Haematology·Lene Molgaard-HansenUNKNOWN Nordic Society of Paediatric Haematology and Oncology (NOPHO)
Jan 20, 2011·Pediatric Blood & Cancer·Simone CesaroGianni Bisogno
Mar 26, 2011·The Journal of Surgical Research·Frankie B FikeCharles L Snyder
May 13, 2011·The New England Journal of Medicine·Scott C HowardChing-Hon Pui
Jun 24, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Daiki MiyataAkira Matsui
Jul 26, 2011·AJR. American Journal of Roentgenology·Alampady Krishna Prasad ShanbhogueNajla Fasih
Sep 29, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mariël L te WinkelMarry M van den Heuvel-Eibrink
Oct 25, 2011·Pediatric Blood & Cancer·Jona HattangadiTorunn Yock
Jan 27, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Stefan D RobertsJerry L Shenep
May 17, 2012·Systematic Reviews·Robert S PhillipsUNKNOWN PICNICC Collaboration

❮ Previous
Next ❯

Citations

Aug 14, 2020·The Journal of Laryngology and Otology·P ZavrasI Psarommatis
Dec 3, 2016·Pediatric Radiology·Susan C ShelmerdineSue C Kaste
Dec 20, 2019·Insights Into Imaging·Trevor GauntSusan C Shelmerdine
May 7, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Brittany K Albers, Geetika Khanna
Nov 25, 2020·Pediatric Clinics of North America·Susan E Pacheco, James M Stark

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.