Imaging of acute and subacute toxicities of cancer therapy in children

Pediatric Radiology
Govind B ChavhanSue C Kaste


Effective cancer therapies have resulted in significant improvement in survival. However, treatment-related acute and subacute complications are a cause of significant morbidity and mortality. Effects of cancer therapy in children can be seen early in the survival period or later in life in almost all organ systems of the body. Many of these conditions are evaluated by imaging and some are diagnosed based on characteristic imaging features. This article aims to discuss acute and subacute toxicities of cancer therapy in children involving multiple organ systems, pulmonary, gastrointestinal, hepatobiliary, genitourinary and musculoskeletal systems with emphasis on those in which imaging plays a role in diagnosis or management. We also discuss the role of imaging and choice of imaging modalities in these conditions.


Aug 1, 1979·International Journal of Radiation Oncology, Biology, Physics·J L RansomC B Pratt
Apr 1, 1996·Radiology·L F Donnelly, C L Morris
Aug 18, 1997·Pediatric Radiology·B D Fletcher
Feb 7, 2001·Pediatric Radiology·M B McCarvilleJ J Jenkins
May 3, 2000·Alimentary Pharmacology & Therapeutics·W K MacNaughton
Feb 13, 2001·British Journal of Haematology·D R HargraveUNKNOWN Medical Research Council Working Party for Childhood Leukaemia
Feb 24, 2001·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·P CzaudernaJ Godziński
Apr 3, 2002·Seminars in Liver Disease·Laurie D DeLeveGeorge B McDonald
Oct 30, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ursula CreutzigThomas Lehrnbecher
Apr 26, 2005·Acta Oncologica·Luis Felipe Fajardo
Jun 14, 2005·Cancer·M Beth McCarvilleJohn T Sandlund
Jan 21, 2006·AJR. American Journal of Roentgenology·Evguenia J KarimovaSue C Kaste
Mar 22, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Daniel S LevineSusan I Blaser
May 22, 2007·Pediatric Blood & Cancer·Christoph HärtelChristian Schultz
Jun 28, 2007·JAMA : the Journal of the American Medical Association·Maud M GeenenFlora E van Leeuwen
Jul 24, 2008·Bone Marrow Transplantation·M MianoUNKNOWN EBMT Paediatric Working Party
Jul 22, 2008·Radiology·Caroline L HollingsworthVinod K Prasad
Feb 25, 2009·European Radiology·Philip J A Robinson
Mar 14, 2009·Advances in Experimental Medicine and Biology·Stéphane Paulus, Simon Dobson
Jul 17, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Amir A BorhaniMichael Nalesnik
Aug 1, 2009·Journal of Pediatric Hematology/oncology·Hana HakimAditya H Gaur
Oct 20, 2010·British Journal of Haematology·Lene Molgaard-HansenUNKNOWN Nordic Society of Paediatric Haematology and Oncology (NOPHO)
Jan 20, 2011·Pediatric Blood & Cancer·Simone CesaroGianni Bisogno
Mar 26, 2011·The Journal of Surgical Research·Frankie B FikeCharles L Snyder
May 13, 2011·The New England Journal of Medicine·Scott C HowardChing-Hon Pui
Jun 24, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Daiki MiyataAkira Matsui
Jul 26, 2011·AJR. American Journal of Roentgenology·Alampady Krishna Prasad ShanbhogueNajla Fasih
Sep 29, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mariël L te WinkelMarry M van den Heuvel-Eibrink
Oct 25, 2011·Pediatric Blood & Cancer·Jona HattangadiTorunn Yock
Jan 27, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Stefan D RobertsJerry L Shenep
May 17, 2012·Systematic Reviews·Robert S PhillipsUNKNOWN PICNICC Collaboration

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