Imaging of Biological Cells Using Luminescent Silver Nanoparticles

Nanoscale Research Letters
Vira KravetsAnatoliy Pinchuk

Abstract

The application of luminescent silver nanoparticles as imaging agents for neural stem and rat basophilic leukemia cells was demonstrated. The experimental size dependence of the extinction and emission spectra for silver nanoparticles were also studied. The nanoparticles were functionalized with fluorescent glycine dimers. Spectral position of the resonance extinction and photoluminescence emission for particles with average diameters ranging from 9 to 32 nm were examined. As the particle size increased, the spectral peaks for both extinction and the intrinsic emission of silver nanoparticles shifted to the red end of the spectrum. The intrinsic photoluminescence of the particles was orders of magnitude weaker and was spectrally separated from the photoluminescence of the glycine dimer ligands. The spectral position of the ligand emission was independent of the particle size; however, the quantum yield of the nanoparticle-ligand system was size-dependent. This was attributed to the enhancement of the ligand's emission caused by the local electric field strength's dependence on the particle size. The maximum quantum yield determined for the nanoparticle-ligand complex was (5.2 ± 0.1) %. The nanoparticles were able to penetrate c...Continue Reading

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Citations

Feb 12, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Victor A ErmakovFrancisco Chagas Marques
Jan 24, 2019·International Journal of Molecular Sciences·Chengzhu LiaoSie Chin Tjong
Jun 27, 2019·Pharmaceutics·Mostafa MabroukDiganta B Das
Sep 17, 2020·The Journal of Chemical Physics·Benjamin EvangelistiAdri C T van Duin
Sep 12, 2017·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Marit KjærvikWolfgang E S Unger
Oct 13, 2020·Biotechnology and Applied Biochemistry·Peng TanSubash C B Gopinath
Mar 14, 2021·Colloids and Surfaces. B, Biointerfaces·Ladislav SvobodaZuzana Vilamová
Oct 11, 2017·The Journal of Physical Chemistry. B·Rosina Ho-WuTheodore Goodson

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Methods Mentioned

BETA
surface plasmon resonance
transmission electron microscopy
confocal microscopy

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