PMID: 15367867Sep 16, 2004Paper

Imaging of peripheral nerve lesions

Current Opinion in Neurology
M Koltzenburg, M Bendszus

Abstract

Clinical investigations of peripheral nerve lesions routinely involve nerve conduction studies and electromyography. Imaging studies are often used to exclude focal mass lesions or external compression and to visualize muscle atrophy. More recently, it has been recognized that magnetic resonance imaging can identify changes in peripheral nerves and secondary neurogenic alterations in skeletal muscle, which may significantly enhance its use in the differential diagnosis of peripheral nerve disease. Acute axonal nerve lesions cause a hyperintense signal on T2-weighted images at and distal to the lesion site, which correlates with Wallerian degeneration and nerve oedema. Superparamagnetic iron oxide particles provide an exciting new tool to detect the invasion of macrophages into the degenerating nerve distal to an axonal lesion. Prolongation of the T2 relaxation time and gadolinium enhancement of denervated muscle develop in parallel to the development of spontaneous activity on electromyography, and are probably the consequence of capillary enlargement and increased muscular blood volume. Magnetic resonance imaging supplements the differential diagnosis of peripheral nerve disease. An advantage over clinical neurophysiological i...Continue Reading

References

Mar 13, 1993·Lancet·A G FillerJ S Tsuruda
Feb 1, 1994·Journal of Applied Physiology·H A Eisenberg, D A Hood
Apr 1, 1993·Radiology·J L FleckensteinP D Purdy
Nov 5, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S PeledF A Jolesz
Nov 14, 2001·Neurology·M Bendszus, M Koltzenburg
Jan 11, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·M Bendszus, M Koltzenburg
Mar 1, 2002·Muscle & Nerve·Gerald A GrantMichel Kliot
Jun 12, 2002·Neurology·M BendszusM Koltzenburg
Jun 5, 2004·Neuroimaging Clinics of North America·Jeffrey G JarvikMichel Kliot
Jun 5, 2004·Neuroimaging Clinics of North America·Gerald A GrantMichel Kliot
Jun 12, 2004·Experimental Neurology·Martin BendszusMartin Koltzenburg

❮ Previous
Next ❯

Citations

Oct 17, 2007·Skeletal Radiology·Andrew J DunnDimitri J Anastakis
Mar 25, 2008·Skeletal Radiology·S KamathP M Hughes
May 7, 2011·Skeletal Radiology·Avneesh ChhabraTheodoros Soldatos
Mar 29, 2008·European Radiology·Gustav AndreisekDominik Weishaupt
Jun 14, 2006·European Journal of Applied Physiology·Min LiuKrista Vandenborne
Aug 26, 2006·Nature Clinical Practice. Neurology·Martin Bendszus, Guido Stoll
Jul 19, 2012·Journal of Computer Assisted Tomography·Pearlene P LeeAvneesh Chhabra
Dec 20, 2012·Investigative Radiology·Roberto GasparottiStefano Ferraresi
Oct 17, 2012·PloS One·Jennifer KollmerMirko Pham
Jun 28, 2011·AJR. American Journal of Roentgenology·Avneesh ChhabraJohn A Carrino
Feb 19, 2016·Journal of Magnetic Resonance Imaging : JMRI·Alain R ViddeleerMatthijs Oudkerk
Feb 24, 2016·Case Reports in Anesthesiology·Paul David WeykerThoha M Pham
Jan 8, 2016·Journal of Molecular Neuroscience : MN·Hai-Cheng HuangChuan-Xiang Li
Oct 12, 2010·Journal of the Neurological Sciences·Thurid SanderChristoph Helmchen
Jun 27, 2006·Clinics in Sports Medicine·Jenny T Bencardino, Zehava Sadka Rosenberg
Dec 23, 2006·Dental Clinics of North America·Christopher J Spencer, Henry A Gremillion
Dec 13, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Simon R PlattG Diane Shelton
Jun 13, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Todd M BishopG Diane Shelton
Oct 16, 2010·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Marie-Noëlle Hébert-BlouinRobert J Spinner
Jun 14, 2015·Clinical Neuroradiology·J KollmerM Pham
Dec 1, 2014·European Radiology·Daniel SchwarzPhilipp Bäumer
Apr 30, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Neil G SimonMichel Kliot
Apr 27, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Christine SievertInés Carrera
Nov 29, 2016·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Betül TepeliOya Ümit Yemişçi
Sep 25, 2014·International Journal of Palliative Nursing·Tarnia Taverner
Aug 8, 2008·Current Opinion in Supportive and Palliative Care·Ralf Baron, Thomas R Tölle
Sep 22, 2007·Current Opinion in Neurology·Martin Koltzenburg, Tarek Yousry
May 14, 2005·Current Opinion in Neurology·Hubertus KöllerHans-Peter Hartung
Jul 22, 2018·Neurology·Jennifer KollmerUte Hegenbart
Aug 15, 2018·Japanese Journal of Radiology·Carmela VisalliIgnazio Salamone
Jan 1, 2021·Current Tissue Microenvironment Reports·Matthew WilcoxJames B Phillips
Mar 2, 2021·Der Radiologe·Jennifer Kollmer, Martin Bendszus

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomegaly

Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.