Imaging of the unstable plaque

International Journal of Cardiology
Kiat Tsong Tan, Gregory Y H Lip

Abstract

Atherosclerosis is now considered a systemic inflammatory disorder affecting the arterial tree. Inflammation plays a role in all stages of the disease, from the initiation of the fatty streak to the final stage of plaque rupture. Atherosclerotic plaques that demonstrate the features of active inflammation are more likely to become symptomatic. In addition to having a higher risk of developing adverse cardiovascular events, patients who have higher indices of inflammation may be more likely to develop restenosis after endovascular stenting. Thus, the identification of the 'inflamed plaque' is the subject of intense research. The detection of the inflamed plaque by the conventional modalities of ultrasound, magnetic resonance imaging, computed tomography and nuclear medicine as well as the novel imaging modalities of optical coherence tomography, near-infrared spectroscopy, thermography and angioscopy will be examined.

References

May 1, 1991·Journal of Vascular and Interventional Radiology : JVIR·D C ReddS L Kaufman
Jun 22, 1999·The New England Journal of Medicine·G D Sloop
Sep 28, 2000·The New England Journal of Medicine·J A GoldsteinW W O'Neill
Oct 9, 2002·The Journal of Experimental Medicine·Steffen MassbergMeinrad Gawaz
Jun 29, 2004·The American Journal of Cardiology·Christophe CaussinJean-François Paul
Aug 27, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Fumio InoueTakahisa Uchiyama
Sep 1, 2004·Journal of the American College of Cardiology·Briain D MacNeillGuillermo J Tearney
Jan 7, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Sei KomatsuKazuhisa Kodama
May 27, 2005·The International Journal of Cardiovascular Imaging·Brad H Thompson, William Stanford
Oct 13, 2005·Lupus·R Gerli, N J Goodson
Nov 5, 2005·Thrombosis and Haemostasis·Kiat T Tan, Gregory Y H Lip
Apr 25, 2006·Journal of the American College of Cardiology·Mohammad MadjidS Ward Casscells
Apr 25, 2006·Journal of the American College of Cardiology·Jay D CaplanJames E Muller
Jun 15, 2007·Journal of the American College of Cardiology·Konstantinos ToutouzasChristodoulos Stefanadis

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