PMID: 9545788Apr 18, 1998Paper

Imaging the tear film and in vivo cornea. Initial results with a modified confocal laser scanning ophthalmoscope

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
J Stave, R Guthoff

Abstract

As the slit-lamp technique is an restrictive method for the in-vivo examination and documentation of the multi-layer structure and the dynamics of the tear film and the cornea, e.g. during wound-healing processes, our aim was to find out whether it is possible to change the confocal laser scanning ophthalmoscope (CLSO; Zeiss) into a high-resolution confocal laser scanning microscope (CLSM) for the visualization of the anterior segments of the eye and the tear film by adapting a special objective system. In order to gain information concerning the function of such a cornea microscope we examined selected patients with erosion or pterygium before and after operation and subsequent phototherapeutic keratectomy (PTK), as well as some in-vitro corneal surfaces after photorefractive keratectomy (PRK). We developed an objective adapter for the CLSO in order to focus the laser beam onto anterior segments of the eye to visualize the tear film and the layer structure of the cornea. By combining the long-distance objective or a contract objective with different zoom-optic lenses it was possible to alter the scan field size and so the magnification of the CLSM by a factor of up to 1000. The CLSM provides a new method for the in-vivo examin...Continue Reading

Citations

May 10, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·R RathF Tost
Jun 24, 2006·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Béla ErdélyiJános Németh
Mar 20, 2018·Biomedical Optics Express·Viacheslav MazlinA Claude Boccara

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