Imaging well-differentiated hepatocellular carcinoma with dynamic triple-phase helical computed tomography

The British Journal of Radiology
C-S LiL-C Chiang

Abstract

To investigate the imaging appearance of well-differentiated hepatocellular carcinoma (HCC) on dynamic CT, a total of 38 histopathologically proven well-differentiated HCC were included in a retrospective study. We reviewed the contrast-enhanced dynamic CT of all 38 tumours for attenuation of each tumour in unenhanced scan, arterial-dominant and delayed portal venous phases. Our results showed that dynamic CT identified 26 (68.4%) out of the 38 lesions. The remaining 12 lesions were isodense compared with surrounding liver parenchyma in each dynamic CT phase. There was no statistically significant difference between the mean size of tumours detected by dynamic CT and that of tumours not detected by dynamic CT (p = 0.1). Of a total of 38 tumours, most were isodense (n = 19) or hypodense (n = 16) in unenhanced scan, mostly hyperdense (n = 18) or isodense (n = 15) in arterial-dominant phase and mostly isodense (n = 22) or hypodense (n = 15) in delayed portal venous phase. Enhancement of tumour was observed in 19 (50.0%) of 38 lesions. In conclusion, the ability of dynamic CT to detect well-differentiated HCC is poor, and negative CT findings cannot exclude the presence of well-differentiated HCC, especially if there is well-ground...Continue Reading

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Citations

Oct 17, 2012·Japanese Journal of Radiology·Akihiro NishieHiroshi Honda
Sep 24, 2011·World Journal of Gastroenterology : WJG·Kazuhiro SaitoKoichi Tokuuye
Nov 22, 2007·AJR. American Journal of Roentgenology·Su Jin KimByung Ihn Choi
Oct 18, 2008·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ran-Chou ChenHsing-Yang Tu
Oct 10, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Kenji KutaraKazushi Asano
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Mar 25, 2008·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Nai-Yuan ChengHsing-Yang Tu

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