Imidazopyridines as a source of biological activity and their pharmacological potentials-Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials

Bioorganic & Medicinal Chemistry
Lucyna Dymińska

Abstract

Derivatives of imidazopyridine are used in medicinal chemistry due to their biological and pharmaceutical properties. This review article presents imidazopyridine pharmacological activity as antiinflammatory, anticancer, antiviral, antiosteoporotic, antiparasitic, and antihypertensive agents by studying its various synthesized derivatives. Some of compounds with imidazopyridine skeleton are used in psychiatry and autoimmune disorders. The presented data suggest that IR and Raman spectra measurements are a good methods for identification and characterization of the compounds containing imidazopyridine core. Two stretching vibrations: νas(Φ) and νs(Φ) are of a diagnostic importance. The appearance of these bands in the IR and Raman spectra of some plants, tissues and pharmaceuticals confirms the presence of imidazopyridine skeleton in these substances.

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Citations

Mar 21, 2017·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Chitrakar Ravi, Subbarayappa Adimurthy
May 2, 2019·Organic & Biomolecular Chemistry·Xue-Mei ZhaoXin-Qi Hao
Jun 1, 2018·Acta Crystallographica. Section E, Crystallographic Communications·Saikat Kumar Seth
May 21, 2020·Acta Crystallographica. Section E, Crystallographic Communications·Zainab JabriKhalid Misbahi
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Mar 21, 2019·The Journal of Organic Chemistry·Lu-Lu TianMao-Ping Song
Oct 24, 2018·The Journal of Organic Chemistry·Shuai LuMao-Ping Song

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