Iminopyridine complexes of manganese, rhenium, and molybdenum derived from amino ester methylserine and peptides Gly-Gly, Gly-Val, and Gly-Gly-Gly: self-assembly of the peptide chains

Inorganic Chemistry
Celedonio M ÁlvarezDaniel Miguel

Abstract

Complexes containing pyridine-2-carboxaldehyde (pyca) ligand acting as κ(2)-(N,O) chelates in [MX(CO)(3)(pyca)] (M = Mn, Re; X = Cl, Br), or [MoX(methallyl)(CO)(2)(pyca)] (X = Cl, Br), are good precursors for iminopyridine complexes derived from amino esters and peptides of formula [MX(CO)(3)(py-2-C(H)═NCHX-COOY)] or [MoX(methallyl)(CO)(2)(py-2-C(H)═NCHX-COOY)], via Schiff condensation of the aldehyde function of pyca with the terminal NH(2) group of the amino ester or peptide. X-ray determinations confirm the structures and show that in solid phase the peptide chains assemble through H-bonds adopting different patterns which depend on the geometry of the metal-ligand fragments. The H-bonding patterns have been analyzed in detail and described by using graph set methods. In most cases, Mo complexes show intramolecular arrangement involving the halogen (Cl or Br) and an NH group of the side chain. For the Mn and Re complexes, the peptide side arms form infinite chains, helices, and rings. In many cases, the terminal carboxylic O-H function is engaged in a "terminal" H-bond with a polar molecule of solvent (THF or acetone), instead of forming the usual head-to-head arrangement found in simple carboxylic acids. For the longer trip...Continue Reading

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Aug 8, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Celedonio M AlvarezDaniel Miguel
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Citations

Mar 23, 2012·Inorganic Chemistry·Celedonio M ÁlvarezJosé A Turiel
Jul 29, 2016·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Taofeng ZhangBin Liu
Dec 10, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Celedonio M ÁlvarezDaniel Miguel
May 31, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Kullapa ChanawannoChristopher J Ziegler
Dec 6, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Celedonio M ÁlvarezDaniel Miguel

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