PMID: 3759252Jan 1, 1986Paper

Imipenem/cilastatin in surgical intensive medicine

Infection
H WenkA Valesky

Abstract

26 patients from the surgical intensive care unit, University Hospital Lübeck, received imipenem/cilastatin for severe abdominal, respiratory or urogenital infections. 500 mg imipenem/cilastatin were infused i.v. over 30 min q. i. d. The treatment was successful in 84,6% of the patients suffering from severe infections. Two cases were considered to be failures. 36 of the 43 isolated pathogens (83.7%) were eliminated. Transitory elevations of liver enzymes were the most frequent side-reactions observed; an increase in serum creatinine, diarrhoea or fungal colonization were less common.

References

May 1, 1985·Antimicrobial Agents and Chemotherapy·B A ZajacR R MacGregor
Oct 1, 1984·European Journal of Clinical Microbiology·I Braveny
Nov 1, 1984·Antimicrobial Agents and Chemotherapy·G L DrusanoS C Schimpff

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