PMID: 7009892Mar 1, 1981Paper

Imipramine--a possible alternative to current therapy for urinary incontinence in the elderly

The Journal of Urology
C M CastledenM J Asher

Abstract

Imipramine was given orally at night to 10 elderly patients with urinary incontinence associated with spontaneous unstable detrusor contractions. The dose was increased for each patient up to a maximum of 150 mg. at night, or until continence was achieved or side effects occurred. Of the 10 patients 6 became continent. In 3 of the 6 patients who underwent repeat cystometry bladder capacity had increased (mean 105 cc), bladder pressure at capacity decreased (mean 18 cm. water) and urethral pressure increased (mean 30 cm. water). There was no correlation between plasma desmethylimipramine and dose, or clinical or urodynamic effect.

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Citations

Dec 1, 1990·Annals of Medicine·G Lose
Sep 1, 1988·The Journal of International Medical Research·R Ruffmann
Nov 1, 1983·Journal of the American Geriatrics Society·M E Williams
Dec 1, 1982·The Journal of Urology·C M CastledenB M Ogden
Jan 12, 1999·British Journal of Urology·A Wagg, J Malone-Lee
Jun 17, 2006·Gynäkologisch-geburtshilfliche Rundschau·Stefano SalvatorePierfrancesco Bolis
Jul 1, 1988·Drug Intelligence & Clinical Pharmacy·G L RomanowskiM I Cahn
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Mar 1, 1983·Journal of the American Geriatrics Society·K K Hui
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Mar 28, 1985·The New England Journal of Medicine·J W Rowe
Nov 1, 1984·The Journal of Urology·I GiljaJ Parazajder
Jun 7, 2011·Annals of Medicine·Ariana L Smith, Alan J Wein
Nov 1, 2010·Female Pelvic Medicine & Reconstructive Surgery·Lior Lowenstein
Mar 31, 2015·Social Psychiatry and Psychiatric Epidemiology·Chia-Lun KuoShu-Wen Cheng
Oct 1, 1988·Journal of the American Geriatrics Society·F C PannillR Davis
Mar 1, 1990·Journal of the American Geriatrics Society·A J Wein
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Feb 23, 1999·The Urologic Clinics of North America·C E Iselin, G D Webster
Dec 13, 2002·The Urologic Clinics of North America·Alan J Wein, Eric S Rovner

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