Immediate and 1-year follow-up with the novel nanosurface modified COBRA PzF stent

Archives of Cardiovascular Diseases
Luc MaillardFrançois Vochelet

Abstract

The COBRA PzF coronary stent, which has a unique nano-coating of Polyzene-F, was developed to reduce the risk of stent thrombosis. To report procedural and 1-year clinical outcomes following COBRA PzF coronary stent implantation in a real-world percutaneous coronary intervention (PCI) registry. All patients assigned to treatment with the COBRA PzF in the GCS Axium Rambot Center, Aix-en-Provence, France between February 2013 to June 2014 were prospectively enrolled. Among 100 patients (71% men, mean±standard error age 71.4±11.0 years), 38% had acute coronary syndromes. The population was consistent with real-world experience and included patients with multiple co-morbidities and 26% with diffuse multivessel disease. A total of 151 lesions were treated with 166 stents, including 26% of lesions with a type B2 or C classification. Pre- and post-procedural quantitative coronary angiography analyses showed a mean acute gain of 2.2±0.2mm. Angiographic success was achieved in all cases. One-year follow-up was available for all patients and the target vessel failure (composite of all-cause mortality, myocardial infarction or target vessel revascularization) rate was 12%, including 2% mortality (end-stage cardiomyopathy), 5% myocardial i...Continue Reading

Citations

Jun 18, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Luc MaillardLoic Belle
Jan 12, 2021·Advanced Drug Delivery Reviews·Jun ChenHo-Wook Jun
Apr 18, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Anne CornelissenAloke Finn
Jun 10, 2021·APL Bioengineering·Aleena Mary CherianDeepthy Menon

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