PMID: 8939836Dec 1, 1996Paper

Immediate and delayed effects of laparoscopic Nissen fundoplication on pulmonary function

Surgical Endoscopy
M AnvariL A Moran

Abstract

An effort was made to assess the respiratory outcomes of laparoscopic Nissen fundoplication (LNF). Prospective follow-up of 69 patients undergoing LNF for gastroesophageal reflux disease. Outcomes included pulmonary function testing, 24-h pH recording, esophageal manometry, and symptom assessment. There was an improvement (p < 0.0001) in heartburn and cough scores. There was a significant fall in spirometry (p < 0001), diffusing capacity (p < 0.0001), and respiratory muscle strength (p < 0.0001) 36 h after surgery, which had returned to baseline by 1 month. At 6 months, the patients (n = 16) with impaired preoperative diffusing capacity showed improvement (17.8 +/- 3.7 to 19.8 +/- 4.6 ml/min/mmHg, p = 0.0245). Patients undergoing LNF have impaired gas exchange before surgery which tends to improve 6 months after surgery. There is an early reversible impairment in respiratory function due to diaphragm dysfunction. Patients with a preoperative 1-s forced expired volume > 1.5, or 50% predicted, are unlikely to develop significant early respiratory complication.

Citations

May 13, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Mirjana MirićDavor Plavec
Jan 28, 2014·International Journal of Surgery·Franklin AdabaCharles S Robertson
Jan 28, 2014·Heart & Lung : the Journal of Critical Care·Richard A Helmers, Krishnaswamy Chandrasekaran
Jun 15, 2007·Journal of Pediatric Surgery·Bethany SlaterCraig T Albanese

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