PMID: 7546396Jun 1, 1995Paper
Immediate-early genes induced by antigen receptor stimulation
Current Opinion in Immunology
K Kelly, U Siebenlist
Abstract
Immediate early genes induced by triggering of the TCR frequently encode proteins that act in signal transduction cascades. Recent advances concerning several immediate-early proteins have been made, including signal-induced regulation of NF-kappa B by I kappa-B, the role of Nur77 in T-cell selection and apoptosis, and the function of PAC-1 in regulating the Ras/ERK pathway.
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