Immobilization tests and periodic leg movements in sleep for the diagnosis of restless leg syndrome

Movement Disorders : Official Journal of the Movement Disorder Society
J MontplaisirG Lavigne

Abstract

Patients with restless leg syndrome (RLS) complain of motor restlessness, usually occurring while they rest in the evening. Two immobilization tests have been described to assess leg restlessness in these patients. In the first test, the patient sits in bed with his or her legs outstretched while electromyograms are recorded from right and left anterior tibialis muscles for an hour (Suggested Immobilization Test [SIT]); in the second test, the legs are immobilized in a stretcher (Forced Immobilization Test [FIT]). In the current study, the SIT and the FIT were compared in patients with RLS and normal control subjects matched for age and sex. More leg movements were seen in patients than in controls during immobilization tests, especially the SIT. These movements were periodic, occurring at a frequency of approximately one every 12 seconds. The SIT (index > 40) was found to discriminate between RLS and control subjects better than the FIT (index > 25). Patients were also recorded during two consecutive nights to measure periodic leg movements in sleep (PLMS). A SIT index greater than 40 and a PLMS index greater than 11 (highest PLMS index of 2 consecutive nights) were found to discriminate patients with RLS from control subjects...Continue Reading

References

Sep 1, 1992·Neurology·G PelletierJ Montplaisir
Jun 1, 1988·Journal of the American Geriatrics Society·S S MoskoJ F Sassin
Jan 1, 1986·Sleep·J Montplaisir, R Godbout
Jul 1, 1985·Journal of Gerontology·S Ancoli-IsraelO J Kaplan
Jan 1, 1995·Movement Disorders : Official Journal of the Movement Disorder Society·S IannacconeS Smirne
Sep 1, 1995·Movement Disorders : Official Journal of the Movement Disorder Society·A S Walters
Jan 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·J MontplaisirP Lespérance

❮ Previous
Next ❯

Citations

Dec 5, 2000·Journal of Neuroscience Research·C J EarleyJ R Connor
Feb 9, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Martin MichaudJacques Montplaisir
Jul 23, 2013·Journal of Neuroscience Methods·Kristyn M RinggoldMark R Opp
Apr 17, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T PenzelUNKNOWN PEARLS Study Group. Pergolide European Australian Restless Legs Study
Sep 2, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R QuatraleE Granieri
Jul 28, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A NicolasJ Montplaisir
Apr 20, 2001·Sleep Medicine·R P. Allen, C J. Earley
Nov 1, 2003·Sleep Medicine·D Garcia-BorregueroY de la Llave
Jun 10, 2010·Nature Reviews. Neurology·Claudia Trenkwalder, Walter Paulus
Jul 4, 2001·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·R P Allen, C J Earley
Jan 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·G G TriblE Auff
Nov 13, 2001·American Journal of Respiratory and Critical Care Medicine·A S Walters
Jun 27, 2009·Neuropsychiatric Disease and Treatment·Giovanni MerlinoGian Luigi Gigli
Dec 1, 2006·Neuropsychiatric Disease and Treatment·Clete A Kushida
Sep 3, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Marco LuigettiGiacomo Della Marca
Jan 15, 2014·Der Nervenarzt·M KrenzerC Trenkwalder
Oct 11, 2014·Clinical Medicine : Journal of the Royal College of Physicians of London·Lisa KlingelhoeferKallol Ray Chaudhuri
Jul 29, 2008·Revue neurologique·E KarroumI Arnulf
Aug 7, 2014·Indian Journal of Pharmacology·Aniruddha BasuHitesh Khurana
Apr 2, 2002·Expert Opinion on Investigational Drugs·Björn Wito Walther
Nov 17, 2015·Current Medical Research and Opinion·Diego Garcia-BorregueroJohn Winkelman
Nov 13, 2004·Current Medical Research and Opinion·K Ray ChaudhuriAdrian Williams
Jul 15, 2015·Sleep Medicine Reviews·Rebekah M AhmedRon R Grunstein
Apr 23, 2004·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·L A MenefeeH Lee
Jul 4, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Akito KumeShuichi Tsutsui
Nov 21, 2007·Sleep Medicine·Jana GodauDaniela Berg
May 22, 2007·Sleep Medicine·Mauro ManconiLuigi Ferini-Strambi
Dec 12, 2007·Clinical Genetics·I PichlerP P Pramstaller
Jan 3, 2007·The American Journal of Medicine·Clete A Kushida
Sep 29, 2004·Psychiatry Research·Katinka TuiskuKristian Wahlbeck
Aug 6, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Wayne Hening
Jun 30, 2004·Sleep Medicine·Diego Garcia-BorregueroJuan José Granizo
Jul 22, 2005·Lancet Neurology·Claudia TrenkwalderArthur S Walters
Oct 1, 2005·International Review of Psychiatry·Sharon Reutens, Perminder S Sachdev

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.