Immune cell signaling in autoimmune diseases

Clinical Immunology : the Official Journal of the Clinical Immunology Society
George C Tsokos, Noel R Rose

Abstract

On September 20, 2016 the American Autoimmune Related Disease Association convened a selected group of 16 experts in Washington DC to discuss current issues and future directions of research in autoimmune diseases from the cell signaling perspective. The major topics considered included new findings on the follicular T cell cells in mice, their metabolic patterns and their control by the newly discovered T follicular regulatory cells. Current work on the metabolic pathways deemed important for the function of T cells was presented. The broader implications of these studies on our understanding of human and murine T regulatory cell and current aspects of B cell biology, innate immunity and organ damage were discussed. This document should provide the reader with a quick update on these topics and help instigate novel studies.

Citations

Nov 28, 2018·Journal of Biomedical Materials Research. Part a·Fei XuHong Zheng
Nov 8, 2018·International Journal of Endocrinology·Maria Giulia SantaguidaMarco Centanni
Feb 15, 2020·Clinical Immunology : the Official Journal of the Clinical Immunology Society·David LanganKamal D Moudgil
Feb 25, 2019·The American Journal of the Medical Sciences·Ziqiang ZhaoJiaqing Shen
Jun 13, 2021·Autoimmunity Reviews·Marc Scherlinger, George C Tsokos

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Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

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