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Immune checkpoint blockade in infectious diseases

Nature Reviews. Immunology

Oct 11, 2017

Michelle N Wykes, Sharon R Lewin

Abstract

The upregulation of immune checkpoint molecules, such as programmed cell death protein 1 (PD1) and cytotoxic T lymphocyte antigen 4 (CTLA4), on immune cells occurs during acute infections, such as malaria, as well as during chronic persistent viral infections, including HIV and hepatiti...read more

Mentioned in this Paper

Immune Response
Pathogenic Aspects
Biochemical Pathway
T-Lymphocyte
Immune Effector Cell
Pathogenesis
Virus Diseases
Cytotoxic T-Lymphocytes
Hepatitis B Virus
HIV Infections
217
6
316
Paper Details
References
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  • Citations23
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Immune checkpoint blockade in infectious diseases

Nature Reviews. Immunology

Oct 11, 2017

Michelle N Wykes, Sharon R Lewin

PMID: 28990586

DOI: 10.1038/nri.2017.112

Abstract

The upregulation of immune checkpoint molecules, such as programmed cell death protein 1 (PD1) and cytotoxic T lymphocyte antigen 4 (CTLA4), on immune cells occurs during acute infections, such as malaria, as well as during chronic persistent viral infections, including HIV and hepatiti...read more

Mentioned in this Paper

Immune Response
Pathogenic Aspects
Biochemical Pathway
T-Lymphocyte
Immune Effector Cell
Pathogenesis
Virus Diseases
Cytotoxic T-Lymphocytes
Hepatitis B Virus
HIV Infections
217
6
316

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References153
  • Citations23
12345...
  • References153
  • Citations23
123
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