PMID: 6972741Jun 1, 1981Paper

Immune complexes, rheumatoid factors, and cellular immunological parameters in patients with giant cell arteritis

Annals of the Rheumatic Diseases
B E MalmvallL M Bjursten

Abstract

Circulating immune complexes were found in 2 of 15 patients with giant cell arteritis (GCA) by using a solid phase Clq enzyme linked immunoabsorbent assay (ELISA). The prevalence in controls was 5%. Rheumatoid factor could be demonstrated in 2 out of 27 patients and in 11% of the controls by using a similar ELISA technique. The prevalence of T cells in blood was similar in 25 patients with GCA and in controls. The blood lymphocyte blastogenic response to the mitogens, phytohaemagglutinin, concanavalin-A, and pokeweed mitogen did not differ in 25 untreated patients compared with controls. Stimulation of lymphocytes by arterial homogenates was tested in 8 patients. In no case could a significant simulation by obtained. We conclude that immune complexes and rheumatoid factors are present in the same low frequency in GCA patients as in the normal population, and that the studied parameters of cellular immunity appear to be normal.

References

Aug 25, 1978·Journal of Neurology·M Mumenthaler
Apr 1, 1975·Annals of the Rheumatic Diseases·B L HazlemanM M Esiri
Jan 1, 1978·Annual Review of Medicine·R E EttlingerL E Ward
Jun 1, 1978·Annals of the Rheumatic Diseases·J R Park, B L Hazleman
Jan 1, 1978·Scandinavian Journal of Rheumatology·B E Malmvall, B A Bengtsson
Jan 1, 1976·Scandinavian Journal of Immunology·S AhlstedtC Wadsworth
Jul 1, 1974·Annals of Internal Medicine·G C LiangM Mannik
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Sep 1, 1967·The Journal of Experimental Medicine·R I Mishell, R W Dutton
Sep 1, 1980·Arthritis and Rheumatism·C C PapaioannouF C McDuffie

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Citations

Jan 1, 1983·Archives of Dermatological Research·H MobackenL A Nilsson
Nov 5, 1997·Survey of Ophthalmology·F D Ghanchi, G N Dutton
Dec 1, 1991·Baillière's Clinical Rheumatology·R Andersson
Dec 1, 1991·Baillière's Clinical Rheumatology·B E Malmvall

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