Immune Dysregulation in the Pathogenesis of Atopic Dermatitis

Dermatitis : Contact, Atopic, Occupational, Drug
Tatyana Gavrilova

Abstract

Atopic dermatitis is a multifactorial disease. Epidermal barrier impairment often plays the initial role in the initiation of the disease. Immune dysregulation of the innate and adaptive immunity plays a central role in the pathogenesis of atopic dermatitis. Alteration of the epidermal microbiome-host interaction serves a catalytic role in propagating this immune response. The understanding of this disease pathogenesis is important in generating treatment options, especially those such as biologic agents that can target a specific immune pathway.

References

Nov 18, 2000·The Journal of Allergy and Clinical Immunology·N YawalkarL R Braathen
Jun 10, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Siegbert RiegBirgit Schittek
Jan 2, 2008·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Byung Eui KimMichael D Howell
May 16, 2008·The Journal of Investigative Dermatology·Sabine AltrichterGeorg Stingl
Oct 3, 2008·The Journal of Investigative Dermatology·Tao ZhengZhou Zhu
Nov 5, 2008·Journal of Lipid Research·Kenneth R Feingold
Dec 25, 2010·Clinical Reviews in Allergy & Immunology·Andreas WollenbergJürgen Schauber
May 18, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Min-Hee OhTao Zheng
Dec 27, 2011·Immunity·Paola Di MeglioFrank O Nestle
Jan 10, 2012·Biochemical and Biophysical Research Communications·Xin YaoAndrew L Durham
Apr 14, 2012·The Journal of Investigative Dermatology·Ferda Cevikbas, Martin Steinhoff
Sep 7, 2012·The Journal of Allergy and Clinical Immunology·Julia K GittlerEmma Guttman-Yassky
Mar 28, 2013·Mediators of Inflammation·Sadaf Kasraie, Thomas Werfel
Sep 3, 2013·Expert Review of Proteomics·Arup K Indra
Oct 8, 2013·The Journal of Allergy and Clinical Immunology·Jonathan I Silverberg, Jon M Hanifin
Nov 19, 2013·Trends in Microbiology·Nina N Schommer, Richard L Gallo
Nov 28, 2013·Pharmaceuticals·Wataru Aoki, Mitsuyoshi Ueda
May 21, 2015·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F S CavalcanteK R N dos Santos
May 28, 2015·The Journal of Allergy and Clinical Immunology·Giulia FornasaMaria Rescigno
Nov 5, 2015·Allergy and Asthma Proceedings·Namjil N TsybikovEli Magen
Mar 18, 2016·Postȩpy dermatologii i alergologii·Małgorzata Marcinkiewicz, Sławomir Majewski
Sep 28, 2016·The Journal of Allergy and Clinical Immunology·Hitokazu EsakiEmma Guttman-Yassky
Oct 4, 2016·The New England Journal of Medicine·Eric L SimpsonUNKNOWN SOLO 1 and SOLO 2 Investigators
Mar 2, 2017·The New England Journal of Medicine·Thomas RuzickaUNKNOWN XCIMA Study Group
Mar 7, 2017·Clinical, Cosmetic and Investigational Dermatology·Uwe Wollina
Mar 10, 2017·Cellular and Molecular Gastroenterology and Hepatology·Katerina TsilingiriMaria Rescigno
Apr 22, 2017·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Saburo SaitoHiroshi Kiyonari
Jun 29, 2017·Journal of Dermatological Science·Katharina BitscharBirgit Schittek
Jun 29, 2017·Immunological Reviews·Atsushi OtsukaKenji Kabashima
Jun 29, 2017·Immunological Reviews·Oscar PalomaresCezmi A Akdis
Jul 7, 2017·International Journal of Immunogenetics·K DežmanM Rijavec

❮ Previous
Next ❯

Citations

Sep 22, 2019·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Elizabeth Huiwen ThamHugo P S Van Bever
Nov 28, 2018·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Johannes WohlrabThomas Werfel
Mar 9, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kinga Fanni TóthAttila Oláh
Mar 17, 2020·Biotechnology Journal·Elizabeth Huiwen ThamIn Young Hwang
Sep 19, 2020·The Journal of Investigative Dermatology·Garrett J PatrickLloyd S Miller
Aug 20, 2019·International Immunopharmacology·Tian TianMinjun Ji
Jul 9, 2021·Frontiers in Cell and Developmental Biology·Chris M Li, Zhibin Chen
Nov 20, 2021·Veterinary Dermatology·Chie Tamamoto-Mochizuki, Thierry Olivry

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Leukemia & Lymphoma
Marta MuzioFederico Caligaris-Cappio
Asian Pacific Journal of Allergy and Immunology
Enza D'AuriaAmilcare Cerri
Proceedings of the National Academy of Sciences of the United States of America
J Marks-KonczalikY Tagaya
Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology
Angela W CoronaJonathan P Godbout
© 2022 Meta ULC. All rights reserved