[Immune reactions to posterior lamellar versus penetrating keratoplasty. A retrospective analysis].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
E BertelmannN Torun

Abstract

Posterior lamellar keratoplasty is a relatively new surgical procedure for replacing the diseased endothelial layer of the cornea with a healthy layer. There are only few data regarding graft rejection in posterior lamellar keratoplasty. The objective of this paper was to compare posterior lamellar keratoplasty with penetrating keratoplasty for the incidence and risk of graft rejection. This retrospective study included a total of 204 consecutive patients who underwent penetrating keratoplasty or posterior lamellar keratoplasty at the Department of Ophthalmology, Charité CVK, between 1999 and 2000 and between 2007 and 2009. Complete data were obtained in 160 cases. Statistical analysis was performed using SPSS (Statistical Package for the Social Sciences), version 12.0. Descriptive statistics, χ(2)-test and mean values were used to describe and assess the data. Out of 160 eyes 29 were treated with posterior lamellar keratoplasty and 131 eyes were treated with penetrating keratoplasty. The incidence of graft rejection was 3.4% in the posterior lamellar group and 29.8% in the penetrating keratoplasty group (χ(2) = 9.02, p < 0.001). Of 44 patients with Fuchs' endothelial dystrophy (FED) 28 underwent posterior lamellar keratoplasty...Continue Reading

References

Nov 1, 1993·Ophthalmology·H M BoisjolyR Roy
Sep 6, 2000·Transplantation·H J Völker-DiebenJ D'Amaro
Apr 16, 2004·Cornea·Gerrit R J MellesCarla P Nieuwendaal
Feb 24, 2005·Cornea·Abdullah Al-TorbakMichael D Wagoner
Apr 4, 2006·Ophthalmology·Stephanie L WatsonJohn K G Dart
Nov 15, 2006·Cornea·Mark S Gorovoy
Dec 13, 2006·Ophthalmology·Steven B Koenig, Douglas J Covert
Sep 26, 2007·Cornea·Bruce D S AllanMargareta Claesson

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Citations

Jun 7, 2013·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C CursiefenL M Heindl
Dec 22, 2012·Case Reports in Ophthalmological Medicine·Enrique O Graue-HernandezArturo Ramirez-Miranda

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