Immune response of Theileria sp.-infected sheep to recombinant Theileria proteins

Annals of the New York Academy of Sciences
Ulrike SeitzerJabbar Ahmed

Abstract

Sheep and goats in northwest China suffer from theileriosis from infection with Theileria sp. (China), resulting in large economic losses. To investigate the immune response to infection with Theileria sp. (China), parameters of cellular and humoral immunity of experimentally infected sheep against two recombinantly expressed Theileria proteins were investigated. The in vitro proliferative response of blood mononuclear cells to a recombinant T. annulata membrane protein and a recombinant Theileria sp. (China) homologue to T. annulata surface protein, both putative membrane proteins, was significantly elevated and significant amounts of specific immunoglobulins were produced against both.

References

Jan 1, 1984·Advances in Parasitology·H Mehlhorn, E Shein
Jun 8, 2002·Parasitology Research·Jabbar AhmedFrans Jongejan
Dec 1, 2006·Annals of the New York Academy of Sciences·Joana P G MirandaUlrike Seitzer
Dec 1, 2006·Annals of the New York Academy of Sciences·Jabbar S AhmedHong Yin

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