Immune responses and expression of immune-related genes in swimming crab Portunus trituberculatus exposed to elevated ambient ammonia-N stress

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Feng YueJian Li

Abstract

The effects of ammonia-N (0, 1, 5 and 20mgL(-1)) on immune responses and immune-related gene expression were determined in swimming crab Portunus trituberculatus. The results showed that the THC and phagocytic activity of P. trituberculatus exposed to 1, 5 and 20mgL(-1) ammonia-N decreased significantly during the experimental time. The antibacterial and bacteriolytic activities decreased significantly to the minimum at 6 or 12h respectively, then recovered to the control level except bacteriolytic activity exposed to 5 and 20mgL(-1) ammonia-N. alpha(2)-macroglobulin (alpha(2)-M) activity of all ammonia-N exposure groups decreased significantly, then recovered to the control level rapidly and tended to be stable after 12h. With crabs exposed to 20mgL(-1) ammonia-N, the gene expression levels of crustin and lysozyme decreased significantly, then recovered to the control level after 12h. ALF expression also decreased significantly when exposed to 5 and 20mgL(-1) ammonia-N, then remained stable and significantly lower than the control group after 6h. In contrast, alpha(2)-M gene expression was induced by ammonia-N exposure significantly. The results suggest that high concentration ammonia-N exposure could reduce the crab immunity ...Continue Reading

References

Sep 13, 2003·Fish & Shellfish Immunology·Rogerio R Sotelo-MundoGloria Yepiz-Plascencia
Jun 18, 2004·Immunological Reviews·Philippe BuletLaure Menin
Aug 25, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Francisco Vargas-AlboresAngélica Avila-Villa
Feb 24, 2007·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Meiling HongYong Chen
Jun 15, 2007·Physiological Genomics·Enrique de la VegaBernard M Degnan
Mar 18, 2008·Developmental and Comparative Immunology·Virginia Brockton, Valerie J Smith

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Citations

May 10, 2011·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Singaram GopalakrishnanKe-Jian Wang
May 7, 2015·Environmental Science and Pollution Research International·Eun Young MinJu-Chan Kang
Jan 10, 2021·Animals : an Open Access Journal From MDPI·Bilal Ahamad ParayMahmoud A O Dawood
Oct 22, 2020·Journal of Invertebrate Pathology·Christopher J Coates, Kenneth Söderhäll

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