Immune responses to fleas in two rodent species differing in natural prevalence of infestation and diversity of flea assemblages

Parasitology Research
Irina S KhokhlovaA Allan Degen

Abstract

We studied in vivo immune response to fleas in two gerbils, Gerbillus dasyurus and Gerbillus andersoni allenbyi, which differed in their natural species richness of flea assemblages and prevalence of infestation. G.dasyurus is parasitized naturally by several flea species, but the prevalence of infestation is low, whereas G. a. allenbyi is parasitized by a single flea species, with high prevalence of infestation. We hypothesized that immunological parameters and the cell-mediated specific immune response to an antigen from an unfamiliar flea species differ between the two gerbil species. Parasitized and control gerbils of both species demonstrated similar, relatively low levels of spontaneous glucose consumption. The same was true for the phytohemagglutinin treatment. Responses to antigen from unfamiliar flea species were higher than both spontaneous glucose consumption and response to phytohemagglutinin in parasitized and control G. a. allenbyi and parasitized G. dasyurus. However, no significant difference in the spontaneous blast transformation index and responses to both phytohemagglutinin and flea antigen was found in control G. dasyurus. The number of white blood cells was significantly lower in control than in parasitize...Continue Reading

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Citations

Mar 17, 2011·Oecologia·Boris R KrasnovSerge Morand
Apr 21, 2007·Parasitology·B R KrasnovA A Degen
Oct 21, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Joëlle Goüy de BellocqBerry Pinshow
Jan 31, 2015·The Journal of Parasitology·Hillary S YoungKristofer M Helgen
Sep 21, 2010·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Irina S KhokhlovaBoris R Krasnov
Jul 19, 2005·Oecologia·Boris R KrasnovGeorgy I Shenbrot
May 26, 2018·Parasitology Research·Luther van der MeschtBoris R Krasnov
Mar 26, 2014·The Journal of Animal Ecology·Justin R St JulianaBoris R Krasnov
Jun 15, 2007·The Journal of Experimental Biology·Irina S KhokhlovaA Allan Degen
Jun 21, 2014·The Journal of Experimental Biology·Elizabeth M DlugoszBoris R Krasnov
Mar 24, 2012·The Journal of Experimental Biology·Irina S KhokhlovaBoris R Krasnov
Nov 11, 2011·The Journal of Experimental Biology·Michael KamA Allan Degen
Apr 14, 2021·International Journal for Parasitology·Boris R KrasnovSonja Matthee

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