Immune signalling by supramolecular assemblies

Immunology
Santosh Kumar, Shweta Jain

Abstract

Formation of supramolecular assemblies appears to be a general mechanism in immune signalling pathways. These supramolecular assemblies appear to form through a nucleated polymerization mechanism. This review examines selected immune signalling pathways that involve supramolecular assemblies, describes the concepts of protein polymerization, and discusses how those concepts of protein polymerization implicate new elegant ways for signal amplification, setting threshold and noise reduction in these pathways.

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Citations

Apr 13, 2021·Journal of Biomedical Science·Sara Socorro FariaKelly Grace Magalhães

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