Immune thrombocytopenic purpura.

Indian Journal of Pediatrics
V GuptaB D Bhatia

Abstract

Immune thrombocytopenic purpura (ITP) is the commonest cause of sudden onset thrombocytopenia in a healthy child. The condition is frequently preceded by a viral infection. The hematological parameters are essentially normal except a low platelet count. Bone marrow examination is not routinely indicated except in specific situations. The pros and cons of drug treatment have been discussed as the disease is benign with excellent prognosis in majority of the cases. The various treatment options including low and high dose steroids, intravenous immunoglobulins and anti D have been discussed at length with other modalities of treatment and role of splenectomy. Current therapeutic options with rituximab and other drugs for stimulating platelet production in chronic cases have also been included in discussion.

References

Jan 1, 1984·The American Journal of Pediatric Hematology/oncology·G R Buchanan, C A Holtkamp
Feb 18, 2003·British Journal of Haematology·UNKNOWN British Committee for Standards in Haematology General Haematology Task Force
Oct 30, 2004·Hematology/oncology Clinics of North America·Michael D Tarantino, George R Buchanan
Jul 4, 2006·Seminars in Hematology·Michael Tarantino
Aug 26, 2006·Pediatric Blood & Cancer·George R Buchanan, Leah Adix
Aug 26, 2006·Pediatric Blood & Cancer·Thomas Kühne
Nov 25, 2006·Hematology·Diane J Nugent
Dec 16, 2006·Pediatric Blood & Cancer·Thomas KühneUNKNOWN Intercontinental Childhood ITP Study Group
Oct 16, 2007·Current Opinion in Hematology·Michael D Tarantino, Paula Hb Bolton-Maggs

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Citations

Jun 8, 2010·Annals of Hematology·Francisco Javier PeñalverUNKNOWN Multi-institutional Retrospective Study on the use of rituximab in refractory AIHA
Jan 29, 2013·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Mohammad Ali MashhadiEbrahim Miri-Moghaddam
Jun 9, 2012·La Revue de médecine interne·O DebouverieO Pourrat
Apr 20, 2011·Journal of Paediatrics and Child Health·Saber HammamiMohamed Neji Guediche

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